| 壳聚糖/羟基磷灰石复合骨折内固定棒材的制备与性能研究 |
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| 引用本文： | 孙珍珍,蔡汝汝,蒲曦鸣,杨云,姚清清,侯振清,张其清.壳聚糖/羟基磷灰石复合骨折内固定棒材的制备与性能研究[J].功能材料,2011,42(1):128-131. |
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| 作者姓名： | 孙珍珍 蔡汝汝 蒲曦鸣 杨云 姚清清 侯振清 张其清 |
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| 作者单位： | 厦门大学生物医学工程研究中心/材料学院福建省生物医学工程重点实验室厦门市生物医学工程技术研究中心;中国医学科学院中国协和医科大学生物医学工程研究所天津市生物医学材料重点实验室; |
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| 基金项目： | “十一五”国家科技支撑计划资助项目(2007BAD07B05); 福建省海洋与渔业局重点资助项目(闽海渔合同号[2008]1-11) |
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| 摘 要： | 采用原位沉析法制备了壳聚糖/羟基磷灰石(CS/HA)复合棒材.用预先沉积的壳聚糖膜将含有Ca、P源的壳聚糖溶液与凝固液隔离,同时控制壳聚糖沉积与羟基磷灰石前驱体转化为羟基磷灰石的过程,使二者得以均匀复合.燃烧试验结果表明无机成分均匀分散于壳聚糖中,FT-IR、XRD和TEM测试证实原位生成羟基磷灰石,弯曲强度测试结果表...
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| 关 键 词： | 壳聚糖 羟基磷灰石 原位沉析 内固定 |
Study on preparation and performance of the CS/HA rods for bone Internal fixation |
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| SUN Zhen-zhen,CAI Ru-ru,PU Xi-ming,YANG Yun,YAO Qing-qing,HOU Zhen-qing,ZHANG Qi-qing.Study on preparation and performance of the CS/HA rods for bone Internal fixation[J].Journal of Functional Materials,2011,42(1):128-131. |
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| Authors: | SUN Zhen-zhen CAI Ru-ru PU Xi-ming YANG Yun YAO Qing-qing HOU Zhen-qing ZHANG Qi-qing |
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| Affiliation: | SUN Zhen-zhen1,CAI Ru-ru1,PU Xi-ming1,YANG Yun1,YAO Qing-qing1,HOU Zhen-qing1,ZHANG Qi-qing1,2 (1.Research Center of Biomedical Engineering/College of Materials,Xiamen University,Key Laboratory of Biomedical Engineering of Fujian Province Research Center of Biomedical Engineering Technology of Xiamen,Xiamen 361005,China,2.Institute of Biomedical Engineering,Chinese Academy of Medical Science,Peking Union Medical College,Tianjin 300192,China) |
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| Abstract: | The CS/HA composites with a high performance were prepared via in situ precipitation.In this method,the calcium and phosphorus precursors were added into the solution of chitosan firstly,dispersed homogeneously.The pre-precipitated CS membrane controlled the process of CS precipitation and transformation of HA from the precursors.The results of burn-out tests indicated that the inorganic component was dispersed uniformly in chitosan matrix.FT-IR,XRD and TEM were carried out to determine the components and m... |
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| Keywords: | chitosan hydroxyapatite in situ precipitation internal fixation |
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