超声造影剂衰减系数随时间变化特性研究

为了研究微泡型超声造影剂对声传播衰减的影响,基于气泡动力学理论模型计算微观粒径变化引起的声传播衰减,推导出超声造影剂衰减系数随时间变化的解析表达式,并构建了实验系统,对超声造影剂的衰减系数进行测量。实验结果验证了理论模型的有效性,以及超声造影剂衰减系数随时间变化呈现出指数衰减规律。该研究为减小超声波的传播衰减和畸变提供了依据,使得超声造影剂有效地应用于超声医学领域。

Study on the Time-dependent Change of Attenuation Coefficient of Ultrasound Contrast Agent

To study the influence of microbubble type ultrasound contrast agent (UCA) on the attenuation of acoustic propagation, based on the theoretical model of bubble dynamics to calculate the attenuation of acoustic propagation due to changes in microscopic particle size, and the analytical expression of the attenuation coefficient of the UCA with time variation was deduced. Moreover, an experimental system was built to measure the attenuation coefficient of the UCA. Experimental results verified the validity of the theoretical model and the exponential decay law of the attenuation coefficient of the UCA over time. This study provides a basis for reducing the propagation attenuation and distortion of ultrasound waves, making the UCA are effectively used in the field of ultrasound medicine.