In vitro performance of magnesium processed by different routes for bone regeneration applications |
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Authors: | M Carboneras BT Peréz-Maceda JA del Valle MC García-Alonso RM Lozano ML Escudero |
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Affiliation: | 1. Unité Matériaux Et Transformations, UMR CNRS 8207, University of Lille, F-59000, Lille, France;2. Department of Mechanical Engineering, National University of Singapore (NUS), 9 Engineering Drive 1, 117576, Singapore |
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Abstract: | Magnesium processed by powder metallurgy (PM) and casting was investigated for potential use in bone regeneration applications. To reduce its corrosion rate, magnesium was surface-modified by a chemical conversion treatment in hydrofluoric acid (HF). In vitro behaviour was evaluated in terms of biodegradation and osteoblastic cell response. The metallurgical route used to produce magnesium has more significant consequences on biodegradation and biocompatibility than the effects of the surface coating. The coated magnesium processed by casting exhibits the best in vitro performance. |
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