羟基磷灰石生物涂层的复合制备与生物相容性

采用等离子喷涂CaHPO4和水热处理复合制备羟基磷灰石生物涂层，研究了羟基磷灰石涂层的结合强度和溶解性，用成骨细胞考察了生物相容性，结果表明，喷涂涂层由C aHPO4,β－Ca2P2O7和α-C3(PO4)2组成，其相比例，结晶性和形貌取决于喷涂电流和喷涂距离；喷涂涂导经过水热处理可转化为针状结晶的缺钙羟基磷灰石，这种羟基磷灰石涂层具有高的结合强度和稳定性，与成骨细胞的生物相容性良好。

Duplex Prepared Hydroxyapatite Coating and Its Biocompatibility

The hydroxyapatite coating was hydrothermally prepared from plasma sprayed CaHPO4 coating and its bonding strength and solubility were studied. The osteoblast culture test was also produced in order to examine the biocompatibility of the coating. The as-sprayed coating consists of CaHPO4, β-Ca2P2O7 and α-Ca3(PO4)2, and the phase ratio, crystallity and morphology are dependent on spraying current and stand-off distance. The as-spayed coating can be converted to calcium-deficient hydroxyapatite coating with needle-like crystals by hydrothermal treatment. The hydrothermally synthesized hydroxyapatite coating having high bonding strength and stability, possesses good biocompatibility with the osteoblast.