Effect of Binder and Geometry of Tablet on Rate of Wear, Hardness and Tensile Strength

The relation of concentration of starch and povidone in tablets of Emcompress and Fast-Flo lactose and the relation of pressure applied to the tablets to wear rate constant, hardness and tensile strength are reported. The extent to which these parameters are changed by concentration and applied pressure is compared. The influence of shape on the wearability of flat face, flat face bevel edge bisect and standard convex tablets with and without a lubricant was studied.