| E1 超声造影剂的非线性参量研究 |
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| 引用本文： | 龚秀芬,叶式公,章东,冯绍松,章瑞铨,王润田,徐智章,王文平,刘利民.E1 超声造影剂的非线性参量研究[J].声学技术,1996(4):1900/7/26-1900/7/28. |
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| 作者姓名： | 龚秀芬 叶式公 章东 冯绍松 章瑞铨 王润田 徐智章 王文平 刘利民 |
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| 作者单位： | 南京大学声学研究所近代声学重点实验室，中科院东海研究站，上海医科大学中山医院 |
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| 摘 要： | 近年来对超声造影剂的研究兴趣日趋增加是由于它有可能改进超声临床诊断的效果。含有微气泡的液体可用作有效的超声造影剂。液体中气泡的存在可提高液体的非线性参量值。本文用检测二次谐波的方法实验上测定了５种超声造影剂的非线性参量：四种含气泡的液体（声振后）和半乳糖Ｅｃｈｏｖｉｓｔ３００。结果表明，含有微气泡的液体具有非常大的非线性参量值。对这种高非线性值的现象文中进行了可能的解释和讨论
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Measurement of nonlinearity parameter of ultrasound contrast agents |
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| GONG Xiufen,YE Shigong,ZHANG Dong,FENG Shaosong,ZHANG Ruiqian,WANG Runtian,XU Zhizhang,WANG Wenping and LIU Liming.Measurement of nonlinearity parameter of ultrasound contrast agents[J].Technical Acoustics,1996(4):1900/7/26-1900/7/28. |
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| Authors: | GONG Xiufen YE Shigong ZHANG Dong FENG Shaosong ZHANG Ruiqian WANG Runtian XU Zhizhang WANG Wenping and LIU Liming |
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| Affiliation: | Instiute of Acoustics, State Key Lab.of Modern Acoustics, Nanjing University, Nanjing. China 210093;Instiute of Acoustics, State Key Lab.of Modern Acoustics, Nanjing University, Nanjing. China 210093;Instiute of Acoustics, State Key Lab.of Modern Acoustics, Nanjing University, Nanjing. China 210093;Shanghai Acoustics Lab.Academia Sinica, China 200032;Shanghai Acoustics Lab.Academia Sinica, China 200032;Shanghai Acoustics Lab.Academia Sinica, China 200032;Zhong Shan Hospital, Shanghai Medical University, China. 200032;Zhong Shan Hospital, Shanghai Medical University, China. 200032;Zhong Shan Hospital, Shanghai Medical University, China. 200032 |
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| Abstract: | The increasing interest in ultrasound contrast agent in recent years is connected with the possible improvement to ultrasonic clinical diagnosis,A liquid containing microbubles is used to be an effective ultrasound contrast agent.The presence of bubbles in a liquid may enhance the nonlinearity parameter of the liquid.This paper is devoted to experimental determination of nonlinearity parameter B/A by using the method of second harmonics detection for five kinds of ultrasound contrast agents:four kinds of aqua with bubbles (after sonicated)and Echovist 300.Results indicate that the values of nonlinearity parameter B/A for liquids with microbubbles are extremely large. Possible explanation of the highly nonlinearity is also discussed. |
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