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超声弹性显微镜成像系统开发与应用的初步研究
引用本文:施俊,郑永平,严壮志,周康源.超声弹性显微镜成像系统开发与应用的初步研究[J].声学技术,2007,26(2):228-233.
作者姓名:施俊  郑永平  严壮志  周康源
作者单位:1. 上海大学通信与信息工程学院,上海,200072
2. 香港理工大学赛马会康复工程中心
3. 中国科学技术大学电子工程与信息科学系,合肥,230027
基金项目:上海市重点学科建设项目;上海市教委资助项目;上海市高校优秀青年教师后备人选科研项目;香港研究资助局资助项目
摘    要:传统的超声弹性成像技术一般使用1MHz~10MHz的超声波,这一频段超声波的空间分辨率在毫米量级,它不能满足对生物组织中微细结构(如皮肤层,关节软骨等)的研究。文中介绍一套新开发的超声弹性显微镜成像系统,并将其初步应用于对关节软骨和老鼠表皮的成像研究中。该系统由加压系统和背向散射超声显微镜系统两部分组成,其中超声探头频率为50MHz。通过对关节软骨和老鼠表皮的成像实验表明,该系统可以清晰的对生物组织中微细结构成像,研究它们的机械特性。

关 键 词:超声  弹性显微镜  关节软骨
文章编号:1000-3630(2007)-02-0228-06
收稿时间:2006-09-28
修稿时间:2006-09-282006-12-12

Development and applications of ultrasound elastomicroscopy
SHI Jun,ZHENG Yong-ping,YAN Zhuang-zhi and ZHOU Kang-yuan.Development and applications of ultrasound elastomicroscopy[J].Technical Acoustics,2007,26(2):228-233.
Authors:SHI Jun  ZHENG Yong-ping  YAN Zhuang-zhi and ZHOU Kang-yuan
Affiliation:1. School of Communication and Information Engineering, Shanghai University, Shanghai 200072, China; 2. Jacky Club Rehabilitation Engineering Center, The Hong Kong Polytechnic University, Hong Kong, China; 3. Department of Electronic Engineering and Information Science, University of Science and Technology of China, Hefei 230027 ,China
Abstract:Traditional elasticity imaging, typically operated in the ultrasound frequency range of 1- 10 MHz, can provide resolutions in the order of millimeters. This is insufficient for observing fine structures of biological tissues such as skin and articular cartilage. In this paper a new ultrasound elastomicroscopy is developed and applied to image the articular cartilage and mouse skin. The system consists of a compression system and a backscatter ultrasound microscope system with an ultrasound transducer of 50 MHz. By imaging the articular cartilage and mouse skin, it has been shown that the system can clearly image the fine structure of biological tissues and study the machine properties.
Keywords:ultrasound  elastomicroscopy  articular cartilage
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