基于火焰加热的微流体器件制造系统

基于玻璃热成型技术设计一种微流体器件的制备系统，该系统基于火焰加热并通过多组电机的顺序控制可实现不同规格微玻璃管的拉制。并通过软件对加热过程中微玻璃管的温度变化建立仿真分析模型，分析加热过程中微玻璃管的温度分布变化，为微玻璃管的加热时间提供借鉴，并对不同加热时间下微玻璃管的软化区域进行探究。通过改变制备系统的加热时间、拉伸电机的转速、加热区域宽度、微玻璃管的型号可拉制出不同型号尺寸的微针、微管道等微流体器件，并利用系统样机进行了基于加热时间、拉制速度、加热宽度的实验，探究各参数对微流体器件形貌尺寸的影响。相比于传统的制备系统，该系统不仅拥有多样化的可调参数，而且可通过更换不同内径的筒夹来实现对不同尺寸微流体器件的制备，使其拉制范围更广。

Microfluidic Device Manufacturing System Based on Flame Heating

A manufacturing system for microfluidic devices was designed based on glass thermoforming technology. The system could draw microglass tubes with different specifications based on flame heating and sequential control of multiple sets of motors. Through software,a simulation analysis model was established for the temperature change of the microglass tube during the heating process,the temperature distribution change of the micro glass tube during the heating process was analyzed, to provide reference for the heating time experiment of the microglass tube, and the microglass tube softening area under different heating times was explored.By changing the heating time of the preparation system, the rotation speed of the stretching motor, the width of the heating area, and the type of the microglass tube,microfluidic devices such as microneedles and microtubes with different sizes could be drawn.Experiments about heating time,drawing speed and heating width were made to explore the effect of various parameters on the morphology and size of microfluidic devices. Compared with traditional manufacturing system, the system not only has a variety of adjustable parameters, but also can realize the preparation of microfluidic devices with different sizes by replacing collets with different inner diameters, so that the drawing range is wider.