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Comparison of the in vitro corrosion behavior of biodegradable pure Zn in SBF, 0.9% NaCl,and DMEM |
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| Authors: | Xinglong Zhu Pushan Guo Lijing Yang Cheng Xu Fang Geng Jianwei Shen Ting Lu Wensheng Sun Zhenlun Song |
| Affiliation: | 1. Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, China
School of Physical Science and Technology, ShanghaiTech University, Shanghai, China University of Chinese Academy of Sciences, Beijing, China;2. Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, China University of Chinese Academy of Sciences, Beijing, China;3. Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, China;4. Medtronic Inc., Minneapolis, Minnesota, USA;5. Ningbo Medical Center Lihuili Hospital, Ningbo, China;6. Ningbo Powerway Alloy Material Co., Ltd., Ningbo, China |
| Abstract: | Zn-based alloys are considered to be the new biodegradable implant materials due to their suitable degradation rate and good biocompatibility. The biocorrosion behavior of pure Zn in 0.9% NaCl, simulated body fluid, and Dulbecco's modified Eagle's medium (DMEM) was investigated by electrochemical and immersion tests. These tests revealed that pure Zn has the lowest corrosion rate in DMEM and the highest in 0.9% NaCl. Aggressive Cl− has an important effect on the corrosion process. Buffering agents, amino acids, and glucose have a close connection with corrosion resistance. Among the three solutions, DMEM with a similar ion concentration and necessary nutriments is recommended as the more suitable choice for estimating biodegradable alloys' in vitro degradation. |
| Keywords: | corrosion behavior electrochemical immersion test in vitro biodegradation pure Zn |