2-氨基-4-硝基咪唑及其衍生物的合成及热分解研究

以4-硝基咪唑为原料,经硝化,重排,还原,得到2-氨基-4-硝基咪唑,并与3-氯-2,4,6-三硝基苯胺进行缩合合成出2-(3-氨基-2,4,6-三硝基)苯胺基-4-硝基咪唑,收率15%,采用核磁共振、质谱、红外进行了结构表征。探讨了还原的选择性和缩合的机理,结果表明,2,4-二硝基咪唑的2位硝基优先被还原。利用DSC研究了2-氨基-4-硝基咪唑和2-(3-氨基-2,4,6-三硝基)苯胺基-4-硝基咪唑的热分解,分解温度分别为236.32℃和244.86℃。

Synthesis and Thermal Behavior of 2-Amino-4-nitroimidazole and its Derivative

2-Amino-4-nitroimidazole was synthesized using 4-nitroimidazole as starting materials,followed by nitration,thermal rearrangement and selective reduction.The condensation of 2-amino-4-nitroimidazole with 3-chloro-2,4,6-trinitrobenzenamine led to obtain 2-(3-amino-2,4,6-trinitro)phenylamino-4-nitroimidazole in 15% yield.Their structures were confirmed by 1H NMR,MS and IR.Selective reduction and condensation reaction mechanism were discussed.Thermal behaviors of 2-amino-4-nitroimidazole and its derivative were studied by DSC,decomposition temperatures are 236.32 ℃ and 244.86 ℃,respectively.