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The phase change thermoelastic analysis of biological tissue with variable thermal properties during cryosurgery
Authors:Xiaoya Li  Pengfei Luo  Qing-Hua Qin
Affiliation:1. State Key Laboratory for Strength and Vibration of Mechanical Structures, Shaanxi Engineering Research Center of Nondestructive Testing and Structural Integrity Evaluation, School of Aerospace, Xi’an Jiaotong University, Xi’an, PR China;2. Research School of Electrical, Energy and Materials Engineering, College of Engineering and Computer Science, Australian National University, Acton, ACT, Australia;3. Research School of Electrical, Energy and Materials Engineering, College of Engineering and Computer Science, Australian National University, Acton, ACT, Australia
Abstract:Abstract

In this work, the coupling phase change heat transfer process and thermal stress behavior of biological tissue during cryosurgery are studied in the context of a generalized thermoelastic theory. The nonlinear governing equations are constructed while considering the variable thermal properties and solved by a time-domain finite element method based on the effective heat capacity formulation. A 2-D tumor and normal tissue model is adopted for simulating the freezing process in cryosurgery. The effects of temperature-dependent thermal properties and relaxation time on the responses of biological tissue are discussed and illustrated graphically.
Keywords:Cryosurgery  finite element method  generalized thermoelastic theory  phase change  variable thermal properties
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