住院2型糖尿病患者甲状腺功能临床分析

目的了解住院2型糖尿病（2-DM）患者甲状腺功能状态。方法检测247例住院的2-DM患者游离三碘甲状腺原氨酸（FT3）、游离甲状腺素（FT4）、促甲状腺素（TSH）、血糖、糖化血红蛋白（HbA1c）、胆固醇、三酰甘油并进行相关分析。结果247例2-DM患者中甲状腺功能正常210例（A组）占85．1％（210／247），37例甲状腺功能异常占14．9％（37／247）中：亚临床甲减27例（B组）占10．9%（27／247）；亚临床甲亢10例（C组）占4．1％（10／247）。甲状腺功能异常发生率女性高于男性（P〈0．05）。3组间年龄、病程、HbA1c、餐后2h血糖、三酰甘油比较差异无统计学意义（P〉0．05）；空腹血糖：A组高于C组（P〈0．05），B组与A、C组比较差异无统计学意义（P〉0．05）；胆固醇：B组高于C组（P〈0．05），A组与B、C组比较差异无统计学意义（P〉0．05）。结论住院2-DM患者的甲状腺功能异常发生率较高，以亚临床甲减为主，且女性居多。

Thyroid Function of Inpatients with Type 2 Diabetes Meilitus

Objective To investigate the changes in thyroid function of patients with type 2 diabetes mellitus （2-DM）. Methods The concentrations of free T3 （FT3）,free T4 （FT4）,thyroid stimulating hormone （TSH）, blood sugar, H bA1c, cholesterol and triglycerides were detected and analyzed in 247 inpatients with 2-DM. Results Thyroid function was normal in 210 （85.10%） of 247 patients （group A）. Among the other 37 （14. 9%） patients with thyroid dysfunction, 27 （10.9 %） had subclinical hypothyroidism （group B） and 10 （4.1%） had hyperthyroid （group C）. The incidence of thyroid dysfunction in female patients was higher than that in male patients（P〈 0.05）. There were no statistical differences in age, disease course, HbAlc, 2-hour postprandial blood glucose and triglycerides among the three groups（P〉0.05）. The levels of fasting blood glucose in group A were higher than those in group C （P〈0.05）, but no significant differences were observed between group B and group A or group C. The cholesterol levels in group B were higher than those in group C,but no statistical differences were found between group A and group B or group C（P〉0.05）. Conclusion The incidence of thyroid dysfunction is high and subclinical hypothyroid is predominant in patients with 2-DM,especially in females.