| THE INHIBITION EFFECT OF ~(211)At-Te COLLOID AND Na~(211) At INJECTIONS ON MURINE EHRLICH ASCITES TUMOR CELLS |
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| 作者姓名： | 王娟 王喜忠 张家藻 王子淑 金建南 张叔渊 许道权 陈文元 周懋伦 |
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| 作者单位： | Sichuan University，Chengdu 610064，China |
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| 摘 要： | Na211 At and 211 At-Te colloid injections are prepared. It has been demonstrated that the 211 At-Te colloid is stable in vivo and vitro, and can be applied in the study of biology and medicine. In the report, the model of Murine Ehrlich Ascites Cells cultured in vivo and vitro is elected for a series of experiments. It has been proved that Na 211At and 211At-Te colloid injections possess an inhibition effect on tumor cells. The inhibition effect was expressed in surviving of the mice and inhibiting growth of tumor as well as the changes of enzyme activity. Meanwhile, it was also noticed that Na 211 At and 211 At-Te colloid injections of various dose inhibited the absorb of pyrimidine nucleosides in Murine Ehrlich Ascites Cells. And the effect isn't reversible. It is closely related to the dose administratered and 50% inhibition rate needs about 1.48×105 Bq/ml culture.
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THE INHIBITION EFFECT OF ~(211)At-Te COLLOID AND Na~(211) At INJECTIONS ON MURINE EHRLICH ASCITES TUMOR CELLS |
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| Wang Juan Wang Xizhong Zhang Jiazao,Wang Zhishu Jin Jiannan Zhang Shuyuan,Xu Daoquan Chen Wenyuan and Zhou Maolun i.THE INHIBITION EFFECT OF ~(211)At-Te COLLOID AND Na~(211) At INJECTIONS ON MURINE EHRLICH ASCITES TUMOR CELLS[J].Nuclear Science and Techniques,1992(1). |
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| Authors: | Wang Juan Wang Xizhong Zhang Jiazao Wang Zhishu Jin Jiannan Zhang Shuyuan Xu Daoquan Chen Wenyuan and Zhou Maolun i |
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| Abstract: | |
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| Keywords: | 211At 211At-Te colloid Absorb Inhibition rate Prolongation rate Enzyme activity |
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