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双基因联合放射提高脑胶质瘤疗效的研究进展
引用本文:徐媛媛,蒋昕,杨磊,王洁,刘芬菊.双基因联合放射提高脑胶质瘤疗效的研究进展[J].辐射研究与辐射工艺学报,2012(5):257-260.
作者姓名:徐媛媛  蒋昕  杨磊  王洁  刘芬菊
作者单位:苏州大学医学部放射医学与防护学院,江苏省放射医学与防护重点实验室,苏州215123
基金项目:国家自然科学基金项目(31270897、30870585)、江苏高校优势学科建设工程项目(PAPD)资助
摘    要:基因方法治疗脑胶质瘤已成为生物学领域研究的热点,而双基因结合治疗研究倍受关注。基因–放射联合成为脑胶质瘤治疗的新思路,它实施放射治疗和基因治疗联合的策略。本工作在综述脑胶质瘤基因治疗研究的基础上,重点阐述双基因与放射联合的特点及最新研究进展。

关 键 词:胶质瘤  放射治疗  基因治疗  双基因

The research progress of double gene combined with radiation for improving glioma curative effect
XU Yuanyuan,JIANG Xin,YANG Lei,WANG Jie,LIU Fenju.The research progress of double gene combined with radiation for improving glioma curative effect[J].Journal of Radiation Research and Radiation Processing,2012(5):257-260.
Authors:XU Yuanyuan  JIANG Xin  YANG Lei  WANG Jie  LIU Fenju
Affiliation:(School of Radiation Medicine and Protection, Medical College of Soochow University, Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection, Suzhou 215123, China)
Abstract:Gene therapy for glioma is becoming more and more popular in the field of biology, and the double gene therapy has attracted much attention. In recent years, the gene-radiation therapy provides a novel possibility for better treatment of glioma, which combine the speciality of both radiation treatment and gene therapy. This review is aimed to summarize the gene therapy of glioma, especially the latest progress of combination of double gene delivery and radiation therapy.
Keywords:Glioma  Radiation therapy  Gene therapy  Double gene
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