有机锡催化合成乙酸苄酯的新工艺

实验以不同类型的有机锡化合物为催化剂,研究了乙酸苄酯的酯化反应,考察了不同类型的有机锡催化剂的催化效果、催化剂用量、反应温度、反应时间、酸醇摩尔比和带水剂等因素对乙酸苄酯收率的影响。实验结果表明,Ph_3SnCl对合成乙酸苄酯有良好的催化活性,在w(催化剂)=1.5%,n(乙酸):n(苯甲醇)=2.5:1,n(甲苯):n(苯甲醇)=0.60,温度110℃,反应150 min条件下,乙酸苄酯收率可达95.8%,且催化剂重复使用5次仍保持较高活性。

NEW SYNTHESIS PROCESS OF BENZYL ACETATE CATALYZED BY ORGANOTIN COMPOUND

The esterification of benzyl alcohol and acetic acid with different types of organotin compounds as catalysts was studied.The effects of factors such as the different types of organic tin cata- lysts,the amount of catalysts,reaction temperature,reaction time,molar ratio of acid to alcohol and the water-carrying agent were investigated in detail.The results showed that Ph_3SnCl exhibited excellent catalytic activity.When the dosage of the catalyst was 1.5% based on the total mass of benzyl alcohol and acetic acid,the molar ratio of acetic acid to benzyl alcohols was 2.5:1,the dosage of toluene was 10 mL (the molar ratio of toluene to benzyl alcohols 0.60) ,the reaction temperature was 110 ℃,and the reaction time was 120 min,the yield of benzyl acetate was 95.8%.The catalyst could be reused for five times without significant yield declining.