| 尖紫蛤糖胺聚糖抑制肿瘤细胞生长作用的研究 |
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| 引用本文： | 刘倩,范秀萍,吴红棉,胡雪琼.尖紫蛤糖胺聚糖抑制肿瘤细胞生长作用的研究[J].现代食品科技,2012,28(4):396-398. |
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| 作者姓名： | 刘倩 范秀萍 吴红棉 胡雪琼 |
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| 作者单位： | 广东海洋大学食品科技学院,广东湛江,524025 |
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| 基金项目： | 广东海洋大学自然科学研究项目 |
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| 摘 要： | 采用四氮唑蓝还原法(MTT法)研究了尖紫蛤糖胺聚糖对人宫颈癌细胞(Hela细胞)、人鼻咽癌细胞(CNE-2Z细胞)、慢性髓性白血病细胞(K562细胞)的体外抗肿瘤活性。结果显示:尖紫蛤糖胺聚糖对三种肿瘤细胞具有较强的抑制能力,并存在一定的量效关系;尖紫蛤糖胺聚糖与阳性药物(5-Fu)合用呈单纯相加作用或增强、协同作用。
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| 关 键 词： | 尖紫蛤 糖胺聚糖 抑瘤率 |
| 收稿时间： | 1/8/2012 12:00:00 AM |
Inhibition Effect of Glycosaminoglycan from Sanguinolaria acutas on the Growth of Tumor Cells |
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| LIU Qian,FAN Xiu-ping,WU Hong-mian and HU Xue-qiong.Inhibition Effect of Glycosaminoglycan from Sanguinolaria acutas on the Growth of Tumor Cells[J].Modern Food Science & Technology,2012,28(4):396-398. |
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| Authors: | LIU Qian FAN Xiu-ping WU Hong-mian and HU Xue-qiong |
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| Affiliation: | (College of Food Science and Technology,Guangdong Ocean University,Guangdong Zhanjiang 524025,China) |
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| Abstract: | The anti-tumor effect of Glycosaminoglycan from sanguinolaria acutas on Hela cell,CNE-2Z cell and K562 cell in vitro were analyzed by MTT colorimetric method.Results showed that the GAG had anti-tumor activity and the anti-tumor effect of GAG ranged with its concentration.In synergistic inhibition effect of GAG with positive drug(5-Fu) on tumor cells have a simple addition effect or synergistic effect. |
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| Keywords: | Sanguinolaria Acutas glycosaminoglycan the rate of anti-tumor |
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