气相色谱-串联质谱法结合QuEChERS方法快速检测柑橘中52种农药多残留

建立气相色谱-串联质谱结合QuEChERS方法快速检测柑橘中52种农药多残留。样品经乙腈提取、无水硫酸镁和氯化钠盐析后，用N-丙基乙二胺(PSA)固相材料分散填料净化，用气相色谱-串联质谱在多反应监测模式(MRM)下分析检测，该方法的检出限(RSN=3)为0.07～5.7μg/kg，平均回收率为77.3%～117.8%，相对标准偏差小于13.8%。该方法简单、快速、安全、便宜、重现性好，适用于柑橘类水果农药多残留检测。

Rapid Determination of 52 Pesticide Residues in Citrus by Gas Chromatography-Tandem Mass Spectrometry Coupled with QuEChER

In this study, an analytical method was established for the determination of 52 pesticide residues in citrus fruits using QuEChERS cleanup and gas chromatography-tandem mass spectrometry (GC-MS/MS). The pesticide residues in citrus fruit samples were extracted into acetonitrile and salted out by anhydrous MgSO4 and NaCl. Then, the pesticide residues in the supernatant after clean-up on the sorbents of N-propyl ethylene diamine (PSA) were subjected to GC-MS/MS analysis under multi-reaction monitoring (MRM) mode. The limit of detection (RSN = 3) of the established method were in the range of 0.07–5.7 μg/kg, and the average recovery rates for 52 pesticide residues in a blank sample were 77.3%–117.8% with a relative standard deviation (RSD) less than 13.8%. Therefore, this method is simple, quick, safe, cheap and reproducible so that it is suitable for the detection of multiple pesticide residues in citrus fruit samples.