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膳食纤维与肠道微生物互作调节食物过敏的研究进展
引用本文:钟菁华,王中亮,武涌,陈红兵.膳食纤维与肠道微生物互作调节食物过敏的研究进展[J].食品科学,2022,43(3):239-248.
作者姓名:钟菁华  王中亮  武涌  陈红兵
作者单位:(1.南昌大学 食品科学与技术国家重点实验室,江西 南昌 330047;2.南昌大学食品学院,江西 南昌 330047;3.江西省食物过敏重点实验室,江西 南昌 330047;4.南昌大学中德联合研究院,江西 南昌 330047)
基金项目:国家自然科学基金面上项目(31872887)
摘    要:食物过敏的发病率逐步上升,遗传之外的影响因素如饮食受到密切关注。其中,高膳食纤维的食物摄入可能通过与肠道菌群互作和调节肠道黏膜免疫的方式来诱导口服耐受和降低食物过敏发生率。本文在阐述膳食纤维、肠道菌群和食物过敏三者的联系及研究现状的基础上,重点讨论膳食纤维通过调节肠道菌群影响食物过敏的发病机制,旨在为研究过敏人群的合理膳食及开发具有改善食物过敏体质的膳食纤维食品提供科学信息。

关 键 词:食物过敏  膳食纤维  肠道微生物  短链脂肪酸  

Dietary Fiber Regulates Food Allergy by Interacting with the Gut Microbiota: A Literature Review
ZHONG Jinghua,WANG Zhongliang,WU Yong,CHEN Hongbing.Dietary Fiber Regulates Food Allergy by Interacting with the Gut Microbiota: A Literature Review[J].Food Science,2022,43(3):239-248.
Authors:ZHONG Jinghua  WANG Zhongliang  WU Yong  CHEN Hongbing
Affiliation:(1. State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; 2. College of Food Science & Technology, Nanchang University, Nanchang 330047, China; 3. Jiangxi Province Key Laboratory of Food Allergy, Nanchang 330047, China; 4. Sino German Joint Research Institute, Nanchang University, Nanchang 330047, China)
Abstract:The prevalence of food allergy is rising and non-genetic factors such as diet have attracted close attention. The intake of high-fiber diets may induce oral tolerance and reduce the incidence of food allergy by interacting with the intestinal microbiota and modulating the intestinal mucosal immunity. This review describes the current status of studies on the interactions among dietary fibers, the gut microbiota and food allergy, with a focus on how dietary fiber affects the onset of food allergy by regulating the gut microbiota. The purpose of this article is to provide scientific information for developing reasonable diets for allergy sufferers and dietary fiber foods with the potential to alleviate food allergy.
Keywords:food allergy  dietary fiber  gut microbiota  short-chain fatty acids  
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