| 西藏干酪乳酸菌降胆固醇特性研究 |
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| 引用本文： | 肖琳琳,董明盛.西藏干酪乳酸菌降胆固醇特性研究[J].食品科学,2003,24(10):142-145. |
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| 作者姓名： | 肖琳琳 董明盛 |
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| 作者单位： | 南京农业大学食品科技学院,南京,210095 |
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| 基金项目： | 江苏高技术研究发展计划(BJ2002322)，国家(863)高技术研究发展计划(2002AA248041) |
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| 摘 要： | 从西藏传统发酵乳(西藏灵菇)中分离筛选到1株高效降胆固醇乳酸菌KM-16。应用VITEK-32全自动微生物分析系统鉴定该菌为干酪乳杆菌(Lactobacillus casei)。在液体培养基中KM-16乳酸菌对降胆固醇达51.8%。用KM-166灌胃高脂血症模型小鼠研究其对血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)的影响。结果表明灌胃14d后,实验组小鼠血清中TC、TG浓度较对照组显著降低(p<0.01),同时HDL-C浓度有所增加,动脉硬化指数(AI)低于对照的水平。
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| 关 键 词： | 西藏灵菇 干酪乳杆菌 降胆固醇乳酸菌 降血脂作用 动物实验 |
| 文章编号： | 1002-6630(2003)10-0142-04 |
Cholesterol-degrading Activity of Lactobacillus casei Isolated from Tibet Koumiss |
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| Xiao Linlin et al.Cholesterol-degrading Activity of Lactobacillus casei Isolated from Tibet Koumiss[J].Food Science,2003,24(10):142-145. |
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| Authors: | Xiao Linlin |
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| Affiliation: | Xiao Linlin et al |
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| Abstract: | Cholesterol-degrading strains KM-16 was isolated from Tibet traditional koumiss.Using VITEK-32 AutomaticMicrobe Analytic Systems,the isolate was identified as lactobacillus casei.In MRS medium,KM-16 strain showed 51.8% ofcholesterol was degraded.The cholesterol-degrading activities of the strains were mainly due to their bile salt coprecipitionactivity and the cholesterol asimilation.The effects of KM-16 on the total serum cholesterol(TC),triglycerids(TG) and high densitycholesterol(HDL-C)were investigated in artificially-induced hyperlipemial mice.The results showed that the mean values for TCand TG concentrations decreased significantly after feeding 14d while HDL-C in serum increased at the same time. |
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| Keywords: | tibet koumiss lactobacillus casei cholesterol degradation hyperlipidemia |
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