| 纳豆激酶的研究现状与展望 |
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| 引用本文： | 王聪,孔繁东,祖国仁,季瑛,白晓天,杜明.纳豆激酶的研究现状与展望[J].食品研究与开发,2004,25(6):17-20. |
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| 作者姓名： | 王聪 孔繁东 祖国仁 季瑛 白晓天 杜明 |
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| 作者单位： | 1. 大连轻工业学院生物与食品工程学院,116034
2. 中国农业大学食品科学与营养工程学院,北京,100083 |
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| 摘 要： | 纳豆激酶是从日本传统食品纳豆中提取的一种枯草杆菌蛋白酶，具有高效的降血栓作用，而且易吸收，无副作用，有望被开发为新一代的口服抗血栓药物。概括了纳豆激酶的基本生化性质，溶血栓作用及机理，介绍了其酶活测定方法和分离纯化方法，并对纳豆激酶的开发应用进行了分析和展望。
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| 关 键 词： | 纳豆激酶 抗血栓药物 口服 研究现状 副作用 分离纯化方法 生化性质 传统食品 溶血栓 枯草杆菌蛋白酶 |
| 修稿时间： | 2004年7月16日 |
THE PRESENT SITUATION AND DEVELOPMENTAL TENDENCY OF NATTOKINASE |
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| WANG Cong KONG Fandong ZU Guoren JI Ying DU Ming BAI Xiaotian.College of Bio&Food Science,Dalian Institute of Light Industry,Dalian,.College of Food Science&Nutritional Engineering,China Agricultural University,Beijing.THE PRESENT SITUATION AND DEVELOPMENTAL TENDENCY OF NATTOKINASE[J].Food Research and Developent,2004,25(6):17-20. |
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| Authors: | WANG Cong KONG Fandong ZU Guoren JI Ying DU Ming BAI XiaotianCollege of Bio&Food Science Dalian Institute of Light Industry Dalian College of Food Science&Nutritional Engineering China Agricultural University Beijing |
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| Affiliation: | WANG Cong1 KONG Fandong1 ZU Guoren1 JI Ying1 DU Ming2 BAI Xiaotian11.College of Bio&Food Science,Dalian Institute of Light Industry,Dalian,1160342.College of Food Science&Nutritional Engineering,China Agricultural University,Beijing,100083 |
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| Abstract: | Nattokinase,a kind of subtilisin,was found in the Japanese fermented soybean food-natto. It can strongly catalyze fibrinolysis in plasma.Nattokinase is hopeful to become a possible drug in the treatment of thrombi because it is safe for health and easy to absorb. In this article,we describe the characters, the thrombolytic mechanism, the measurements of the fibrinolytic activity,purification of nattokinase. And the development of using nattokinase is included. |
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| Keywords: | nattokinase anti-thrombi measurements of enzymatic activity purification |
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