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| 条斑紫菜酶解多肽的保健功能作用 | |
| 引用本文： | 任姗姗,李鹏高,张淑华,唐玉平,肖忠新,吴惠惠,甄亚平,魏守刚. 条斑紫菜酶解多肽的保健功能作用[J]. 食品研究与开发, 2011, 32(2): 38-41 |
| 作者姓名： | 任姗姗 李鹏高 张淑华 唐玉平 肖忠新 吴惠惠 甄亚平 魏守刚 |
| 作者单位： | 1. 首都医科大学,公共卫生与家庭医学学院营养与食品卫生系,北京,100069 2. 首都医科大学,燕京医学院,北京101300 3. 首都医科大学,临床检验中心,北京,100069 |
| 摘 要： | 通过体外观察条斑紫菜酶解多肽(Peptides from Porphyrayezoensis,PPY)在大鼠主动脉环上拮抗去氧肾上腺素(PE)、KCl和血管紧张素I(AngI)的收缩血管作用,研究PPY的血管舒张作用及机制。结果表明:PPY可显著舒张PE、KCl和Ang I收缩的内皮完整的血管环及张PE预收缩的内皮去除的血管环,且一氧化氮合酶抑制剂L-NAME不能抑制PPY的舒血管作用。因此,PPY的舒血管作用可能是非内皮依赖性的,可能既有抑制血管平滑肌细胞受体操纵性钙通道又有抑制电压依赖性钙通道的作用。 |
| 关 键 词： | 条斑紫菜 胃蛋白酶 多肽 主动脉血管环 血管舒张 |
Vasodilatation Effect of the Peptides from Porphyra Yezoensis |
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| REN Shan-shan,LI Peng-gao,ZHANG Shu-hu,TANG Yu-ping,XIAO Zhong-xin,WU Hui-hui,ZHEN Ya-ping,WEI Shou-gang. Vasodilatation Effect of the Peptides from Porphyra Yezoensis[J]. Food Research and Developent, 2011, 32(2): 38-41 | |
| Authors: | REN Shan-shan LI Peng-gao ZHANG Shu-hu TANG Yu-ping XIAO Zhong-xin WU Hui-hui ZHEN Ya-ping WEI Shou-gang |
| Affiliation: | REN Shan-shan1,LI Peng-gao1,*,ZHANG Shu-hua1,TANG Yu-ping2,XIAO Zhong-xin1,WU Hui-hui1,ZHEN Ya-ping3,WEI Shou-gang1 (1.Department of Nutrition and Food Hygiene,School of Public Health and Family Medicine,Beijing 100069,China,2.Yanjing Medical School,Beijing 101300,3.Clinical Detection Center,Capital Medical University,China) |
| Abstract: | The effect of the peptides from Porphyra yezoensis(PPY) by pepsin hydrolyzation on the contraction-relaxation reaction of the aortic rings from rats were examined by preconstricted with phenylephrine(PE),KCl and Angiotensin I(Ang I),then different concentrations of the PPY were added and the changes in the tension of the ring was monitored.The results showed that cumulative addition of the PPY produced a significant dilation effect against the preconstricted aorta rings with endothelium by either PE,KCl or ... |
| Keywords: | Porphyra yezoensis pepsin peptides aorta ring vasodilatation |
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