In vivo effect of oat cereal β‐glucan on metabolic indexes and satiety‐related hormones in diet‐induced obesity C57‐Bl mice |
| |
Authors: | Lijun Tang Jiaojiao Shi Yi Chen |
| |
Affiliation: | 1. Department of General Surgery, Chengdu Military General Hospital, , Chengdu, P. R. China;2. Department of Clinical Nutrition, Chengdu Military General Hospital, , Chengdu, P. R. China |
| |
Abstract: | This study explored the dose‐dependent effect of oat cereal β‐glucan on improving metabolic indexes of obesity mice. C57‐Bl mice were randomized to chow diet (N) group and high fat diet group and other three doses of oat β‐glucan groups (low β‐glucan, medium β‐glucan, and high β‐glucan). Energy intake, glucose, lipids, and appetite related hormones were tested. Dose‐dependent relation was observed on oat β‐glucan doses and body weight change, average energy intake, total cholesterol, HDL cholesterol, plasma neural peptide Y, arcuate neural peptide Y mRNA, and arcuate neural peptide Y receptor 2 mRNA level. Oat β‐glucan helped to increase plasma peptide Y‐Y and intestine peptide Y‐Y expression in obesity mice. |
| |
Keywords: | Diet‐induced obesity GLP‐1 β ‐Glucan NPY PYY3– 36 |
|
|