多重免疫层析试纸辅助食品安全快速检测的研究进展

快速、灵敏检测食品中各类危害因子是保障食品安全，提高人类健康水平的关键所在。免疫层析试纸条具有成本低廉、操作简单、检测时间短、不依赖复杂设备和专业技术人员等优点，是食品安全现场快速筛查检测的主要技术手段。多重免疫层析试纸可提高检测通量，缩短总体分析时间，为食品中多种危害因子的同时检测提供技术保障。作者介绍了5种常用的信号输出模式（比色、荧光、表面增强拉曼散射、化学发光和磁信号），并简述了上述信号输出方式整合多重免疫层析技术同时检测食品危害因子的研究进展，旨在为多重免疫层析试纸的设计、构建及应用提供一定的理论依据。

Research Progress of Multiplex Immunochromatographic Test Strips for Rapid Food Safety Detection

Rapid and sensitive detection of various hazard factors in food is the key to ensure food safety and improve human health. Immunochromatographic test strip(ICTS) has become the most popular technique for rapid screening and on-site detection of food safety, exhibiting the advantages of low cost, simple operation, short assay time and no need of complex equipment and professional technicians. Particularly, the emergence of multiplex ICTS greatly improves the detection flux and shortens the overall analysis time, providing an effective technical support for simultaneous detection of various hazard factors in food. In this paper, five common signal output modes (colorimetry, fluorescence, and surface enhanced Raman scattering, chemiluminescence and magnetic signal) were introduced, the latest research progress on simultaneous detection of food hazard factors by integrating the above-mentioned signal outputs with multiplex ICTS platform was reviewed. The article aims to provide a certain theoretical guidance for the design and construction of multiplex ICTS technology and its application in food safety analysis.