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| 红树林放线菌的筛选与抗真菌和抗肿瘤活性的测定 | |
| 引用本文： | 李蓉,张京良,江晓路,管华诗.红树林放线菌的筛选与抗真菌和抗肿瘤活性的测定[J].食品与生物技术学报,2010,29(1):94-97. |
| 作者姓名： | 李蓉 张京良 江晓路 管华诗 |
| 作者单位： | 1. 中国海洋大学,食品科学与工程学院,山东,青岛,266003;中国海洋大学,医药学院,山东,青岛,266003 2. 中国海洋大学,食品科学与工程学院,山东,青岛,266003 3. 中国海洋大学,医药学院,山东,青岛,266003 |
| 基金项目： | 国家自然科学基金项目 |
| 摘 要： | 通过从深圳福田红树林根际于不同季节采集的3份土样和2份水样中分离得到95株放线菌,94%的放线菌为链霉菌属。测定95株放线菌发酵液对9种病原真菌的抗菌活性,其中31.6%的放线菌发酵液有不同程度的抗病原真菌作用。同时采用MTT法测定了它们对肺癌细胞A549、白血病细胞株K562两种肿瘤细胞的细胞毒活性,其中21%放线菌发酵液具有细胞毒活性。s33、s62、s65和s68这个4株放线菌发酵液具有抑制5种以上真菌的作用,并且对两种肿瘤细胞株均有作用。 |
| 关 键 词： | 红树林 放线菌 抗真菌活性 抗肿瘤活性 |
The Antifungal and Antitumor Activities of the Isolated Mangrove Forest Actinomycetes |
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| LI Rong,ZHANG Jing-liang,JIANG Xiao-lu and GUAN Hua-shi.The Antifungal and Antitumor Activities of the Isolated Mangrove Forest Actinomycetes[J].Journal of Food Science and Biotechnology,2010,29(1):94-97. | |
| Authors: | LI Rong ZHANG Jing-liang JIANG Xiao-lu and GUAN Hua-shi |
| Affiliation: | LI Rong1,2,ZHANG Jing-liang1,JIANG Xiao-lu1,GUAN Hua-shi2(1.College of Food Science , Engineering,Ocean University of China,Qingdao 266003,China,2.School of Medicine , Pharmaceutics,China) |
| Abstract: | The obective of this study is to isolate mangrove forest derived actinomyces strains for obtaining the bioactive metabolite producing strains to investigate antifungal and anti-tumor active metabolites.For this,actinomyces strains were isolated by single colony isolation technique.The antifungal activity was assayed by paper method.The anti-tumor activity was assayed by MTT method.Ninety-five strains of actinomyces were isolated from 3 soil samples and 2 water samples collected from a mangrove forest in Fut... |
| Keywords: | mangrove forest actinomyces antifungal activity antitumor activity |
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