Phytochemical and biological investigation of <Emphasis Type="Italic">Stevia rebaudiana</Emphasis> Bertoni; 1-labdane-type diterpene |
| |
| Authors: | Nabaweya A Ibrahim Souad El-Gengaihi H Motawe S A Riad |
| |
| Affiliation: | (1) Pharmacognosy Department, National Research Center, Dokki, Cairo, Egypt;(2) Medicinal and Aromatic Plants Department, National Research Center, Dokki, Cairo, Egypt |
| |
| Abstract: | Five labdane diterpenoids, austroinulin, iso-austroinulin, sterebin E, sterebin E acetate, and sterebin A acetate, along with hydrocarbons, aliphatic alcohols, β-amyrin,
β-sitosterol and stigmasterol were isolated from the chloroform soluble fraction of the methanol extract of Stevia rebaudiana leaves. Chlorogenic and caffeic acids were isolated from the EtOAc fraction. All the isolated compounds were identified using
spectral tools. The chloroform and methanol extracts proved significant anti-inflammatory effect and caused marked inhibition
of carrageenan-induced paw oedema in rats. |
| |
| Keywords: | Stevia rebaudiana Labdane diterpenes Chlorogenic acid Caffeic acid Anti-inflammatory |
| 本文献已被 SpringerLink 等数据库收录！ |
|
