改性硅藻土吸附壳聚糖-胍盐微球及其在抗菌纸中的应用

采用离子交联法制备了壳聚糖-胍盐纳米微球复合抗菌剂，采用阴离子表面活性剂十二烷基磺酸钠对硅藻土进行改性，用改性硅藻土对壳聚糖-胍盐微球复合抗菌剂进行吸附，制备了改性硅藻土吸附抗菌剂，研究了硅藻土改性前后对壳聚糖-胍盐微球的吸附行为。红外光谱分析表明，壳聚糖与胍盐复合后没有产生新的特征峰，只是主要特征峰发生了位移，说明二者是通过物理交联而结合在一起。硅藻土对微球的吸附基本在10 min之内达到平衡，并且改性后的硅藻土对微球的吸附量有所增加。将含有硅藻土/壳聚糖-胍盐微球的涂料涂在纸张表面制备抗菌纸，由抗菌实验发现该抗菌纸对大肠杆菌和金黄色葡萄球菌都具有较好的抑制作用。

Adsorption of Chitosan-guanidine Salt Nanoparticles on Modified Diatomite and Its Application in Antibacterial Paper

The chitosan-guanidine salt nanoparticles were prepared by ionic gelation method, and the characterization of the nanoparticles was determinated by FT-IR. Meanwhile, the diatomite was modified using the sodium dodecyl sulfate (SDS), and the adsorption of chitosan-guanidine salt nanoparticles on the modified and native diatomite were studied. The results showed that no new peaks were found from the complex of chitosan and guanidine salt, and the characteristic peaks of chitosan only shifted, which indicated that chitosan and guanidine salt were bonded together by physical crosslinking.The adsorption equilibrium time of the nanoparticles on the surface of modified diatomite was estimated to be about 10 min, and the adsorption amount increased when the diatomite was modified. The antibacterial paper was prepared by coating the diatomite absorbed the chitosan-guanidine salt nanoparticles on the surface of base paper. According to the disc diffusion method, the antibacterial paper exhibited remarkable antibacterial activity against Staphylococcus aureus and Escherichia coli.