| 金属有机骨架载体固定化生物酶的研究进展 |
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| 引用本文： | 张帅,王悦,王艳,赵宁,张娜,辛嘉英.金属有机骨架载体固定化生物酶的研究进展[J].食品工业科技,2022,43(2):463-471. |
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| 作者姓名： | 张帅 王悦 王艳 赵宁 张娜 辛嘉英 |
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| 作者单位： | 哈尔滨商业大学，食品科学与工程重点实验室，黑龙江哈尔滨 150076 |
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| 基金项目： | 国家自然科学基金项目(21573055);哈尔滨商业大学青年创新人才项目青年后备人才专项(2019CX33);2019年度中央支持地方高校改革发展资金人才培养项目;黑龙江省自然科学基金项目(LH2020F008)。 |
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| 摘 要： | 金属有机骨架（Metal-Organic Frameworks, MOFs）是金属中心与有机配体通过配位作用自组装形成的多孔晶态材料。MOFs具有稳定性强、大比表面积、高孔隙率、可重复使用等特点，作为一种新型固定化载体材料，具有广泛的应用前景。本文主要从MOFs载体固定化生物酶的合成方法、MOFs-生物酶复合材料的特性和应用等方面进行总结分析，并对MOFs载体固定化生物酶的将来研究方向进行了展望，为后续开发研究和在生物与医药行业应用提供了理论依据。
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| 关 键 词： | 金属有机骨架 固定化酶 共固定化 金属有机骨架-生物酶复合材料 |
| 收稿时间： | 2021-06-23 |
Research Progress on Immobilization of Biological Enzymes on Metalorganic Framework Carriers |
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| ZHANG Shuai,WANG Yue,WANG Yan,ZHAO Ning,ZHANG Na,XIN Jiaying.Research Progress on Immobilization of Biological Enzymes on Metalorganic Framework Carriers[J].Science and Technology of Food Industry,2022,43(2):463-471. |
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| Authors: | ZHANG Shuai WANG Yue WANG Yan ZHAO Ning ZHANG Na XIN Jiaying |
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| Affiliation: | Key Laboratory for Food Science and Engineering, Harbin University of Commerce, Harbin 150076, China |
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| Abstract: | Metal-Organic Frameworks (MOFs) are porous crystalline materials formed by self-assembly of metal centers and organic ligands through coordination. MOFs have the characteristics of strong stability, large specific surface area, high porosity, and reusability. As a new type of immobilized carrier material, it has a wide range of application prospects. In this article, the synthesis method of biological enzyme immobilized on MOFs carrier is mainly summarized and analyzed, the characteristics and application of MOFs-biological enzyme composite material, and the future research direction of the synthetic method of enzyme immobilized on MOFs carrier are prospected. A theoretical basis would be provided for the development research and applications in the biological and pharmaceutical industries. |
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| Keywords: | metal-organic frameworks(MOFs) immobilized enzymes co-immobilization metal organic frameworksbiological enzyme composite materials |
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