| 乳铁蛋白的特性、分离纯化方法及特点 |
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| 引用本文： | 张东送,庞广昌,刘萍,王彦.乳铁蛋白的特性、分离纯化方法及特点[J].食品科技,2004(5):95-98. |
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| 作者姓名： | 张东送 庞广昌 刘萍 王彦 |
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| 作者单位： | 1. 天津商学院生物工程系,天津·300134
2. 海军后勤学院,天津·300450 |
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| 基金项目： | 国家自然科学基金资助项目(30170685) |
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| 摘 要： | 乳铁蛋白是一种铁结合性糖蛋白,在初乳中含量较高,乳铁蛋白具有多种生物学功能,如抗菌性、抗氧化、抗病毒、抗癌症等。乳铁蛋白的分离纯化方法较多,就吸附色谱法、离子交换色谱法、亲和色谱法、固定化单克隆抗体法、超滤法、盐析法等进行了概述,并就其工业化生产方法进行了展望。
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| 关 键 词： | 乳铁蛋白 分离纯化 工业化 |
| 文章编号： | 1005-9989(2004)05-0095-04 |
| 修稿时间： | 2003年11月10 |
Characteristic, isolation and purification methods of Lactoferrin |
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| ZHANG Dong-song PANG Guang-chang LIU Ping WANG Yan.Characteristic, isolation and purification methods of Lactoferrin[J].Food Science and Technology,2004(5):95-98. |
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| Authors: | ZHANG Dong-song PANG Guang-chang LIU Ping WANG Yan |
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| Affiliation: | ZHANG Dong-song1 PANG Guang-chang1 LIU Ping2 WANG Yan2 |
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| Abstract: | Lactoferrin, an iron-binding glycoprotein, has many biological functions. Such as antibacterial, antioxidant, antiviral and anticancer etc. Its content in the colostrums is the highest. There are many methods for isolation and purification of lactoferrin. This paper gives an overview of the adsorption chromatography, ion exchange chromatography, affinity chromatography, immobilized monoclonal antibodies, ultrafiltration and salting-out. The prospects of the methods of production lactoferrin on a large scale is also summed up. |
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| Keywords: | Lactoferrin (Lf) isolation and purification industrialization |
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