红曲霉的麦角固醇研究

在红曲霉生理活性研究中，发现８株红曲霉分离株均能产生麦角固醇，其中Ｍｏｎａｓｃｕｓａｎｄａ６２５菌株１００ｇ干菌体可得２ｇ左右，最高可达３ｇ。产麦角固醇最适培养基为大米粉。发酵周期９６ｈ。粗提样品的麦角固醇紫外吸收值与标准样品一致。该菌株兼能产生红曲色素，发酵液色价可达１００以上。

Research on Production of Ergosterol from Monascus

n the researches of Monascus physiological active constituent,eight strains of Monascus were screened which porduce ergosterol. Typically, the strain Monascus anka 625 gives an ergosterol yield of to 2g/100g dry biomass and the maximum yield is 3g/100g dry biomass. Optimum medium, fermentation cycle and optimum PH for ergosterol production are rice powder, 96hr.and 5.5～7.0 respectively. The UV-absorption peak of the crude product by extraction and crystollization is the same as that of standard sample.Each strain above-mentionde can produce monascourubin simultaneously.The color standard of fermented filtrate can reach up to 100.