Effect of grape seed oil supplementation on plasma lipid profiles in rats |
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| Authors: | Dae-Jung Kim Geonuk Jeon Jeehye Sung Sea-Kwan Oh Ha-Cheol Hong Junsoo Lee |
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| Affiliation: | 2. Rural Development Administration, National Institute of Crop Science, Suwon, Gyeonggi, 441-857, Korea
1. Department of Food Science and Technology, College of Agriculture, Chungbuk National University, Cheongju, Chungbuk, 361-763, Korea
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| Abstract: | The purpose of the study was to investigate the comparative effects of feeding of grape seed oil (GSO), soybean oil (SO),
and lard on plasma lipid profile in rats. Lard fed diets increased body weight gain in rats and resulted in negative effects
on lipoprotein metabolism. However, the GSO fed rats had a significant reduction in total cholesterol (TC, 60.6 mg/dL), low
density lipoprotein cholesterol (LDLC, 16.8 mg/dL), and atherogenic index (AI, 0.9), and the ratio of high density lipoprotein
cholesterol (HDLC) to TC (0.5) was significantly higher than those of SO and lard groups. These data suggest that GSO supplementation
has significant health benefits through favorable alterations in plasma lipid profiles compared to SO and lard fed rats. GSO
may be good dietary oil and may provide health benefits in hyperlipidemia and related complications. |
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