抗菌整理剂DBPMA的合成及其杀菌性能

以丙烯酰氯、二甲氨基乙醇与氯化苄为原料,合成新型季铵阳离子单体N,N-二甲基,N-苄基,N-丙烯酸酯基氯化铵(DBPMA)。研究了物料比、反应温度、反应时间、反应溶剂对DBPMA转化率的影响,确定出合成DBPMA的最佳工艺。在此工艺条件下,生成季铵盐的转化率为82.1%。探索DBPMA对金黄色葡萄球菌(ATCC6538)的杀菌性能。结果表明:DBPMA的杀菌性能明显优于传统杀菌剂1227;DBPMA在25℃下的临界胶束浓度(CMC)比十二烷基三甲基溴化铵(DTAB)的低。

Preparation and sterilization of quaternary ammonium cationic monomer DBPMA

A new monomer named quaternary cation N, N-dimethyl, N- benzyl, N-acrylate ammonium chloride (DBPMA) is prepared from acryloyl chloride ethanol dimethylamine and benzyl chloride. The effects of the mole ratio of materials, reaction temperature, reaction time, and solvent on the yield were discussed. In the best reaction conditions, the yield of DBPMA is 82.1%. The bactericidal activity on ATCC6538 bacteria of DBPMA were also studied. The results show that the bactericidal activity of DBPMA is better than that of bactericide 1227. At 25℃, the critical micelle concentration (CMC) of DBPMA is much lower than that of dodecyl trimethyl ammonium bromide (DTAB).