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纳米分散高含量叶黄素微囊化的研究
引用本文:周迪,邵斌,许新德,周玉春,刘爱琴,代志凯.纳米分散高含量叶黄素微囊化的研究[J].中国食品添加剂,2012(1):60-65.
作者姓名:周迪  邵斌  许新德  周玉春  刘爱琴  代志凯
作者单位:浙江医药股份有限公司新昌制药厂,新昌,312500
摘    要:叶黄素不溶于水,微溶于植物油,有限的溶解性和对氧化的高敏感性,阻碍了合成得到的粗产品在食品和饲料染色中的直接使用,为增加得色量并增加可吸收性和生物利用率,必须将活性物质的粒径减小到10μm以下,甚至有的达到了纳米级,因为叶黄素的着色效力和生物利用率与其在介质中的粒径和分散性直接相关,为此本文研究了以叶黄素为原料,通过单因素实验,分析了油、溶解温度、时间、喷雾干燥工艺对微囊化叶黄素产品的影响,确定了瞬时高温油溶和喷雾冷凝法微囊化叶黄素新工艺;并通过正交实验,从产品感观质量和稳定性入手,确定了合理的水溶性5%叶黄素微囊化产品配方,解决了高含量叶黄素产品的稳定性、异构和高脂溶难吸收的三大难题。

关 键 词:叶黄素  瞬时高温油溶法  微胶囊化  雾喷冷凝法  高含量

Research on high lutein content microencapsulate by nano-disperse
ZHOU Di , SHAO Bin , XU Xin-de , ZHOU Yu-chun , LIU Ai-qing , DAI Zhi-kai.Research on high lutein content microencapsulate by nano-disperse[J].China Food Additives,2012(1):60-65.
Authors:ZHOU Di  SHAO Bin  XU Xin-de  ZHOU Yu-chun  LIU Ai-qing  DAI Zhi-kai
Affiliation:(Zhejiang Medicine Co.,Ltd.Xinchang Pharmaceutical Factory,Xinchang 312500)
Abstract:Lutein’s insolubility in water,slight solubility in vegetable oils,and high sensitivity to oxidation inhibit its crude products from being directly applied as dyes in the food and feed industry.Research showed that if the size of the active substance is reduced to 10 microns or to the nanometer level,the coloring effect and absorbance all increased.This is because the coloring effects of lutein and its bioavailability are correlated with its particle size.By a single factor experiment and analysis,oil,solution temperature,time,and spray-drying process are selected as the main factors.By orthogonal experiment,combined with sensory quality and stability,the formula for 5% water-soluble lutein microencapsulated products is optimized.It solved three major problems of high concentrated lutein products:stability,heterogeneous and difficult solubility in fat.
Keywords:Lutein  high-temperature oil-soluble instantaneous method  microencapsulation  spray fog condensation method  high-content
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