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Endogenous formaldehyde level of foods and its biological significance
Authors:L Trézl  A Csiba  S Juhász  M Szentgy?rgyi  G Lombai  L Hullán and A Juhász
Affiliation:(1) Technical University of Budapest, Department of Organic Chemical Technology, Müegyetem rkp. 3, H-1111 Budapest, Hungary, HU;(2) Veterinary and Food Control Station, Lehel u. 43 – 47, H-1135 Budapest, Hungary, HU;(3) National Oncological Institute, Ráth G. u. 7/9, H-1122 Budapest, Hungary, HU
Abstract: Formaldehyde was measured in different food samples based on its reaction with hydralazine to form s-triazolo-(3,4-α)-phthalazine(Tri-P). Formaldehyde reacts with hydralazine under mild acidic conditions to form Tri-P. The reaction products were separated by reversed-phase, high-performance liquid chromatography. The method of sample preparation and chromatography are reviewed and the analytical method validated. Using the discussed methods we measured formaldehyde levels in 23 animals and 22 vegetable and fruit samples. Formaldehyde levels were one and a half times higher in vegetable samples compared to meat samples. Received: 23 December 1996 / Revised version: 17 March 1997
Keywords:  Formaldehyde levels  Determination  Food
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