Renal excretion of antioxidative constituents from red beet in humans |
| |
Affiliation: | 1. Institute of Nutrition, Friedrich-Schiller-University, Dornburger Strasse 29, D-07743 Jena, Germany;2. Institute of Food Technology, Section Plant Foodstuff Technology, Hohenheim University, August-von-Hartmann-Strasse 3, D-70599 Stuttgart, Germany;3. Institute of Nutrition, Justus-Liebig-University, Wilhelm Strasse 20, D-35392 Giessen, Germany;4. Solvay Pharmaceuticals GmbH, Hans-Boeckler-Allee 20, D-30173 Hannover, Germany |
| |
Abstract: | The aim of the present study was to assess the renal excretion of red beet juice (RBJ) antioxidants in six healthy humans. After a single oral dose of RBJ. The pharmacokinetic parameters obtained from urine were compared to those obtained after ingestion of water on an intra-individual basis. Urine was collected in intervals up to 24 h post-intake. After RBJ ingestion, the betacyanins betanin and isobetanin were excreted in the volunteers’ urine (0.28% of the administered dose) and unambiguously identified by HPLC–ESI-MS/MS. Compared to the ingestion of water, RBJ consumption resulted in a significantly increased urinary excretion of total phenolics (51.1% of the administered phenolics) and other antioxidant compounds (43.9% of the administered compounds) within 24 h. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|