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L.casei Zhang对小鼠T淋巴细胞亚群及血清IgG和肠黏膜SIgA的影响
引用本文:张和平,张七斤,孟和毕力格,任贵强,阿木尔吉日嘎拉.L.casei Zhang对小鼠T淋巴细胞亚群及血清IgG和肠黏膜SIgA的影响[J].中国乳品工业,2006,34(10):4-8.
作者姓名:张和平  张七斤  孟和毕力格  任贵强  阿木尔吉日嘎拉
作者单位:内蒙古农业大学,乳品生物技术与工程教育部重点实验室,内蒙古,呼和浩特,010018
基金项目:国家自然科学基金;教育部科学技术研究重点项目;教育部春晖计划项目;内蒙古虚拟乳业研究院研究项目
摘    要:对从内蒙古传统发酵酸马奶中分离筛选的L.casei Zhang对小鼠T淋巴细胞亚群、血清IgG和肠黏膜SIgA的影响进行了研究。结果表明,L.casei Zhang可以显著提高小鼠外周血中CD^3+、CD^4+、CD^8+的比例,优化了CD^4+/CD^8+比值.同时L.casei Zhang可以显著增加小鼠血清IgG质量浓度和小鼠肠膝膜SIgA质量浓度。这些结果说明了L.casei Zhang对小鼠的细胞免疫、体液免疫及肠黏膜局部免疫具有调节功能。

关 键 词:T淋巴细胞亚群  免疫调节
文章编号:1001-2230(2006)10-0004-05
收稿时间:2006-09-01
修稿时间:2006年9月1日

Effect of oral administration of L.casei Zhang on T-lymphocyte subclass,serum IgG and intestinal mucous SIgA of mouse
ZHANG He-ping,ZHANG Qi-jin,MEHEBILIGE,REN Gui-qiang,AMRJRGL.Effect of oral administration of L.casei Zhang on T-lymphocyte subclass,serum IgG and intestinal mucous SIgA of mouse[J].China Dairy Industry,2006,34(10):4-8.
Authors:ZHANG He-ping  ZHANG Qi-jin  MEHEBILIGE  REN Gui-qiang  AMRJRGL
Affiliation:Key Lab. of Dairy Biotechnology and Bioengineer, Education Ministry of China, Inner Mongolia Agricultural University, Huhhot 010018, China
Abstract:Effect of oral administration of L.casei Zhang isolated from home-made koumiss of Inner Mongolia on T-lymphocyte subclass, serum IgG and intestinal mucous SIgA of mouse were studied. Research results indicated that oral administration of L.casei Zhang could increase significantly the percentage of CD3+?CD4+ and CD8+,level of serum IgG and intestinal mucous SIgA of mouse,and optimized the ratio of CD4+/CD8+ of T-lymphocyte. These results explained that L.casei Zhang had the regulating function of the cell immunity, the humoural immunity and the intestinal mucous local immunity to mouse.
Keywords:L  casei Zhang
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