微量元素与早产婴幼儿生长发育的相关性

早产是新生儿和 5 岁以下儿童死亡的主要原因,同时作为一种常见的临床不良妊娠结局,不仅增加了母婴短期和长期并发症的风险,而且给个人、家庭和社会造成巨大负担,其发病原因及机制较为复杂,其中母体血液微量元素变化对胎儿发育有着非常重要的影响,微量元素的不平衡,可能导致不良妊娠结局。关于微量元素对早产婴幼儿的作用研究甚少,故本文结合近些年国内外关于微量元素应用的研究,综述了微量元素(铁、铜、锌、硒、锰5种)与早产婴幼儿生长发育的关系,以及微量元素影响早产发生的作用机制(炎症反应、氧化应激、内分泌调节机制),以期为微量元素在早产婴幼儿的生长发育研究中提供一定的理论指导依据。

Research progress on the correlation between trace elements and growth and development of premature infants

Preterm birth is a newborn and the leading cause of death in children under 5 years of age, at the same time, as a kind of common clinical adverse pregnancy outcomes, not only increase the risk of maternal and infant short-term and long-term complications, and poses a great burden to individuals, families and society, its etiology and mechanism of more complex, the maternal blood trace elements changes have a very important impact on fetal development, imbalance of trace elements may result in adverse pregnancy outcomes. Research on trace elements in preterm infants and young children, so this paper research on trace elements application at home and abroad in recent years, summarized the trace elements (iron, copper, zinc, selenium, manganese) and premature infant growth and development, the relationship between trace elements and influence mechanism of action of preterm birth occurred (inflammation, oxidative stress, endocrine regulation mechanism), in order to trace elements in the study of preterm infant"s growth to provide certain theoretical guidance basis.