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液质联用技术在生物毒素食品安全检测分析中的应用
引用本文:王 婵,孙兴权,吴远高,代 弟,刘慧颖,张 彧,曹际娟. 液质联用技术在生物毒素食品安全检测分析中的应用[J]. 食品安全质量检测学报, 2015, 6(1): 3-9
作者姓名:王 婵  孙兴权  吴远高  代 弟  刘慧颖  张 彧  曹际娟
作者单位:大连工业大学, 辽宁出入境检验检疫局,辽宁出入境检验检疫局,塔城出入境检验检疫局,辽宁出入境检验检疫局,辽宁出入境检验检疫局,大连工业大学,辽宁出入境检验检疫局
基金项目:质检公益性行业科研专项(201310141)
摘    要:生物毒素是自然界一种重要的生命现象,是人们探讨生命科学奥秘和开发新药的重要工具和物质基础,也是食品安全领域的重点防治对象。真菌毒素和海洋生物毒素是与食品安全相关的两类生物毒素,二者均具有毒性强、污染面广的特点,对人类健康具有极大的危害。在生物毒素众多分析检测手段中,液质联用技术因灵敏、高效等特点而被广泛应用。本文以液质联用技术为切入点,综述了该技术用于生物毒素食品安全检测分析的研究与应用进展,同时对相关的样品处理技术研究也进行了概要介绍。

关 键 词:真菌毒素   贝类毒素   河鲀鱼毒素   西加鱼毒素   液质联用技术   样品处理
收稿时间:2014-11-12
修稿时间:2015-01-17

Applications of liquid chromatograhpy coupled with mass spectrometry in the detection of biological toxin in food safety testing
WANG Chan,SUN Xing-Quan,WU Yuan-Gao,DAI Di,LIU Hui-Ying,ZHANG Yu and CAO Ji-Juan. Applications of liquid chromatograhpy coupled with mass spectrometry in the detection of biological toxin in food safety testing[J]. Journal of Food Safety & Quality, 2015, 6(1): 3-9
Authors:WANG Chan  SUN Xing-Quan  WU Yuan-Gao  DAI Di  LIU Hui-Ying  ZHANG Yu  CAO Ji-Juan
Affiliation:Dalian Polytechnic University, Liaoning Entry-Exit Inspection and Quarantine Bureau,Liaoning Entry-Exit Inspection and Quarantine Bureau,Tacheng Entry-Exit Inspection and Quarantine Bureau,Liaoning Entry-Exit Inspection and Quarantine Bureau,Liaoning Entry-Exit Inspection and Quarantine Bureau,Dalian Polytechnic University and Liaoning Entry-Exit Inspection and Quarantine Bureau
Abstract:Biological toxin is a kind of important life phenomenon in nature, an important tool and the material basis to explore the secrets of life science and development of new drugs, and is also a key preventive treatment object in the field of food safety. Mycotoxin and marine biotoxins which are two kinds of natural toxic substances associated with food safety, have the characteristics of strong toxicity and pollute widely and a great harm to human health. Among the detection means of mycotoxin and marine biotoxin, the technique of liquid chromatography coupled with mass spectrometry (LC-MS) is widely used for its sensitive and efficient characteristics. Based on the LC-MS technique as a breakthrough point, its application in biological toxins related to food safety testing analysis in recent years were reviewed, as well as the related sample processing technology progress.
Keywords:mycotoxin   shellfish toxin   tetrodotoxin    ciguatoxin   liquid chromatography couple to mass spectrometry   sample processing
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