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基于自组装分子印迹膜的胆固醇电化学传感器
引用本文:薛茜男,边超,任振兴,卞贺明,韩泾鸿,夏善红.基于自组装分子印迹膜的胆固醇电化学传感器[J].仪表技术与传感器,2009(Z1).
作者姓名:薛茜男  边超  任振兴  卞贺明  韩泾鸿  夏善红
作者单位:1. 中国科学院电子学研究所传感技术联合国家重点实验室北方基地,北京,100190;中国科学院研究生院,北京,100039
2. 中国科学院电子学研究所传感技术联合国家重点实验室北方基地,北京,100190
基金项目:国家自然科学基金项目 
摘    要:基于自组装技术在丝网印金电极表面制备分子印迹膜,研制胆固醇电化学仿生传感器.采用循环伏安分析法对电极修饰过程的电化学特性进行表征,采用计时电流法对胆固醇传感器的浓度响应特性进行检测.将传感器对0~700 nM不同浓度胆固醇进行检测,线性范围为100~700 nM,灵敏度为-2.4 nA/nM.

关 键 词:分子印迹  自组装单层膜  胆固醇  电化学传感器

Electrochemical Sensor for Cholesterol Detection Based on Molecular Imprinting Self-assembled Film
XUE Qian-nan,BIAN Chao,REN Zhen-xing,BIAN He-ming,HAN Jing-hong,XIA Shan-hong.Electrochemical Sensor for Cholesterol Detection Based on Molecular Imprinting Self-assembled Film[J].Instrument Technique and Sensor,2009(Z1).
Authors:XUE Qian-nan  BIAN Chao  REN Zhen-xing  BIAN He-ming  HAN Jing-hong  XIA Shan-hong
Abstract:An electrochemical bionic sensor for cholesterol detection was developed with molecular imprinting self-assembled film deposited on the screen printed gold electrode. The electrochemical characteristics of the electrode during modification were studied by cyclic voltammetry technique. The response of the sensor to the concentration of cholesterol was detected by chronoamperometric measurements. Cholesterol between 0 and 700nM were detected by this sensor. The linearity range is from 100 to 700 nM with the sensitivity of -2.4nA/μM.
Keywords:molecular imprinting  self-assembled monolayer  cholesterol  electrochemical sensor
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