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Comparison of Polyphenol Profile and Inhibitory Activities Against Oxidation and α‐Glucosidase in Mulberry (Genus Morus) Cultivars from China
Authors:Qing Jin  Jiufang Yang  Liyan Ma  Jieling Cai  Jingming Li
Affiliation:1. College of Food Science and Nutritional Engineering, China Agricultural Univ, Beijing, China;2. Supervision & Testing Center for Agricultural Products Quality, Ministry of Agriculture, Beijing, China;3. Guangdong Mulberry Wine Industry Co.Ltd, Shantou, Guangdong, China
Abstract:Mulberry (genus Morus) is a significant source of polyphenols, which can promote positive effects on human health. China has various mulberry cultivars, however, many Chinese mulberry cultivars have been only minimally studied. To solve this lack of research, 8 mulberry cultivars (Da10, Tang10, Yueshen74, Yuefenshen, Longsang, Ningxia1hao, Taiwanguosang, and Baiyuwang) from 4 regions of China were assessed to determine their polyphenol profiles using HPLC‐MS/MS and then tested for their antioxidant and anti‐α‐glucosidase activities in vitro. A total of 18 nonanthocyanins and 4 anthocyanins were quantified in mulberry cultivars; among these polyphenols, chlorogenic acid, quercetin 3‐O‐rutinoside, and cyanidin 3‐O‐glucoside were confirmed as the major phenolic acid, flavonol derivative, and anthocyanin, respectively. Two types of stilbene compounds, piceid, and piceatannol, were detected for the 1st time in all mulberry cultivars. Moreover, the methanolic extracts of different mulberry cultivars showed disparate antioxidant and α‐glucosidase inhibitory activities, and this discrepancy was mainly attributed to varying the anthocyanin content. Based on our results, Taiwanguosang is proposed to be a good candidate suitable for further process due to its high level of anthocyanins.
Keywords:antioxidant activity  α  ‐glucosidase  HPLC‐MS/MS  mulberry cultivar  polyphenols
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