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Front Cover: Design of Highly Potent,Dual‐Acting and Central‐Nervous‐System‐Penetrating HIV‐1 Protease Inhibitors with Excellent Potency against Multidrug‐Resistant HIV‐1 Variants (ChemMedChem 8/2018) |
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| Authors: | Prof. Dr. Arun K. Ghosh Dr. Kalapala Venkateswara Rao Dr. Prasanth R. Nyalapatla Dr. Satish Kovela Dr. Margherita Brindisi Dr. Heather L. Osswald Dr. Bhavanam Sekhara Reddy Dr. Johnson Agniswamy Yuan‐Fang Wang Dr. Manabu Aoki Shin‐ichiro Hattori Prof. Dr. Irene T. Weber Prof. Dr. Hiroaki Mitsuya |
| Affiliation: | 1. Department of Chemistry and Department of Medicinal Chemistry, Purdue University, West Lafayette, IN, USA;2. Departments of Biology and Chemistry, Molecular Basis of Disease, Georgia State University, Atlanta, GA, USA;3. Departments of Hematology and Infectious Diseases, Kumamoto University School of Medicine, Kumamoto, Japan;4. Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, National Cancer Institute, Bethesda, MD, USA;5. Center for Clinical Sciences, National Center for Global Heath and Medicine, Tokyo, Japan |
| Abstract: | |
| Keywords: | antiviral agents brain penetration drug resistance HIV-1 protease structure-based design |