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Tracking Protein S‐Fatty Acylation with Proteomics
Authors:Prof. Dr. Ruth Birner‐Gruenberger  Prof. Dr. Rolf Breinbauer
Affiliation:1. Research Unit Functional Proteomics and Metabolic Pathways, Institute of Pathology, Medical University Graz and, Omics Center Graz, BioTechMed-Graz, Stiftintalstrasse 24, Graz, Austria;2. Institute of Organic Chemistry, BioTechMed-Graz, Graz University of Technology, Stremayrgasse 9, Graz, Austria
Abstract:Recently, Hang and co‐workers developed “acyl‐PEG exchange” (APE), which allows the investigation of protein S‐fatty acylation with mass‐tag labelling and gel electrophoresis, methods that are accessible to any biochemistry laboratory.
Keywords:cysteine  lipoproteins  palmitoylation  post-translational modification  proteomics
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