| 多糖与肠道菌群相互作用的研究进展 |
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| 引用本文： | 刘荣瑜,王昊,张子依,宋冬雪,陈锦瑞,汲晨锋. 多糖与肠道菌群相互作用的研究进展[J]. 食品科学, 2022, 43(5): 363-373. DOI: 10.7506/spkx1002-6630-20201113-147 |
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| 作者姓名： | 刘荣瑜 王昊 张子依 宋冬雪 陈锦瑞 汲晨锋 |
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| 作者单位： | （1.哈尔滨商业大学药物工程技术研究中心，黑龙江 哈尔滨 150076；2.哈尔滨商业大学 抗肿瘤天然药物教育部工程研究中心，黑龙江 哈尔滨 150076） |
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| 基金项目： | 黑龙江省自然科学基金项目（LH2020H071；H2015088）；黑龙江省中医药管理局科技计划项目（ZHY2020-175）；黑龙江省普通高等学校青年创新人才培养计划项目（UNPYSCT-2018139） |
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| 摘 要： | 多糖是由10个以上的单糖分子通过缩合、失水而成的高分子聚合物,是构成生命体的基本物质之一.大多数多糖不能被人类基因组中编码的酶降解.肠道菌群由寄生在宿主胃肠道内的多种微生物构成.肠道菌群中的拟杆菌门、厚壁菌门、少量放线菌门和变形菌门能够分泌多糖降解酶降解多糖,促进人体对多糖的消化吸收.多糖中不可被直接消化的成分和发酵产...
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| 关 键 词： | 多糖 肠道菌群 调节 代谢 短链脂肪酸 |
Progress in Understanding Interaction of Polysaccharides with Intestinal Flora |
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| LIU Rongyu,WANG Hao,ZHANG Ziyi,SONG Dongxue,CHEN Jinrui,JI Chenfeng. Progress in Understanding Interaction of Polysaccharides with Intestinal Flora[J]. Food Science, 2022, 43(5): 363-373. DOI: 10.7506/spkx1002-6630-20201113-147 |
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| Authors: | LIU Rongyu WANG Hao ZHANG Ziyi SONG Dongxue CHEN Jinrui JI Chenfeng |
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| Affiliation: | (1. Engineering Research Center for Medicine, Harbin University of Commerce, Harbin 150076, China; 2. Engineering Research Center of Natural Anticancer Drugs, Ministry of Education, Harbin University of Commerce, Harbin 150076, China) |
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| Abstract: | A polysaccharide is a macromolecular polymer composed of more than 10 monosaccharide molecules through condensation and dehydration, and it is an essential substance for life. However, most plant polysaccharides cannot be digested by enzymes encoded by the human genome. The intestinal flora consists of a variety of microorganisms that reside in the gastrointestinal tract of the host, including Bacteroidetes and Firmicutes as well as lesser quantities of Actinobacteria and Protebacteria, which can secrete polysaccharide-degrading enzymes to promote the digestion and absorption of polysaccharides. Non-digestible polysaccharides and short-chain fatty acids (SCFAs) in the fermentation products can further regulate the composition of the intestinal flora, improve intestinal function, and participate in regulating the expression of anti-pathogenic?microorganism, anti-inflammatory, anti-tumor genes, thereby treating diseases and maintaining health. This article summarizes recent progress in understanding the interaction between polysaccharides and the intestinal flora, which will provide a scientific basis for further studies on human health and rational diets. |
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| Keywords: | polysaccharide intestinal flora regulation metabolism short-chain fatty acids, |
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