| 搅拌生物反应器混合特性的数值模拟与实验研究 |
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| 引用本文： | 洪厚胜,张庆文,万红贵,欧阳平凯. 搅拌生物反应器混合特性的数值模拟与实验研究[J]. 过程工程学报, 2005, 5(2): 131-134 |
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| 作者姓名： | 洪厚胜 张庆文 万红贵 欧阳平凯 |
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| 作者单位： | 南京工业大学制药与生命科学学院 |
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| 摘 要： | 以工程流体计算软件CFX-4.4为工具，对不同规模的机械搅拌生物反应器的混合特性进行数值模拟，研究了不同操作条件下反应器混合时间的变化规律. 采用pH电极在位监测[H+]的方法实验测定混合时间. 模拟结果与实验测定值之间的误差随反应器容积增大而逐渐减小，对容积为25 m3的反应器误差小于11.6%.
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| 关 键 词： | 搅拌生物反应器 混合时间 计算流体力学 数值模拟 |
| 文章编号： | 1009-606X(2005)02-0131-04 |
| 修稿时间： | 2004-07-29 |
Numerical Simulation and Experimental Study on Mixing Characteristics of Stirred Bioreactor |
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| HONG Hou-sheng,ZHANG Qing-wen,WAN Hong-gui,OUYANG Ping-kai. Numerical Simulation and Experimental Study on Mixing Characteristics of Stirred Bioreactor[J]. Chinese Journal of Process Engineering, 2005, 5(2): 131-134 |
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| Authors: | HONG Hou-sheng ZHANG Qing-wen WAN Hong-gui OUYANG Ping-kai |
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| Affiliation: | College of Pharmacy and Life Science, Nanjing University of Technology |
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| Abstract: | By commercial CFD package CFX-4.4, mixing characteristics of stirred bioreactor were simulated and the mixing time variation under various operation conditions was investigated. The liquid mixing time was measured by means of detecting the concentration variety of [H+] with a pH probe. The deviation between simulation and experiment becomes smaller as the bioreactor volume is increased, and the error for 25 m3 bioreactor is less than 11.6%. |
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| Keywords: | stirred bioreactor mixing time computational fluid dynamics numerical simulation |
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