1. Department of Internal Medicine, Division of Nephrology, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada;2. Department of Renal Medicine, Division of Medicine, Tan Tock Seng Hospital, Singapore
Abstract:
Adrenal insufficiency is a complication of chronic corticosteroid therapy. Unexplained hypotension may be a manifestation of an adrenal insufficient state in patients with a history of corticosteroid therapy on hemodialysis. We present a series of five cases of patients on nocturnal home hemodialysis with hypotension as the main manifestation of adrenal insufficiency. Unexplained hypotension in patients with a history of corticosteroid therapy should prompt the managing clinician to consider adrenal insufficiency as a possible cause.