| 利福平分子印迹聚合物的制备及其吸附行为 |
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| 引用本文： | 张成丽,周艳梅,雷建都,马同森,马光辉,苏志国. 利福平分子印迹聚合物的制备及其吸附行为[J]. 过程工程学报, 2009, 9(3): 608-612 |
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| 作者姓名： | 张成丽 周艳梅 雷建都 马同森 马光辉 苏志国 |
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| 作者单位： | 河南大学化学化工学院,河南,开封,475004;中国科学院过程工程研究所生化工程国家重点实验室,北京,100190 |
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| 基金项目： | 国家自然科学基金杰出青年科学基金，国家高技术研究发展计划(863计划)，河南省教育厅自然科学基金，北京市自然科学基金 |
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| 摘 要： | 以利福平为模板分子、甲基丙烯酸为功能单体、乙二醇二甲基丙烯酸酯为交联剂，制备了利福平分子印迹聚合物. 采用平衡结合方法和Scatchard模型评价了该聚合物的结合特性，考察了其吸附行为. 结果表明，利福平分子印迹聚合物中形成了两类不同的结合位点，得到高亲和力结合位点的离解常数和最大表观结合量分别为31.5 mg/mL和23.34 mg/g，低亲和力结合位点的离解常数和最大表观结合量分别为9.22 mg/mL和12.86 mg/g. 实验结果显示，利福平分子印迹聚合物对利福平呈现出了高的选择吸附特性.
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| 关 键 词： | 分子印迹聚合物 利福平 识别机理 选择性 |
| 收稿时间： | 2008-12-12 |
| 修稿时间： | 2009-03-20 |
Synthesis of Molecularly Imprinted Polymer for Rifampicin and Its Adsorption |
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| ZHANG Cheng-li,ZHOU Yan-mei,LEI Jian-du,MA Tong-sen,MA Guang-hui,SU Zhi-guo. Synthesis of Molecularly Imprinted Polymer for Rifampicin and Its Adsorption[J]. Chinese Journal of Process Engineering, 2009, 9(3): 608-612 |
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| Authors: | ZHANG Cheng-li ZHOU Yan-mei LEI Jian-du MA Tong-sen MA Guang-hui SU Zhi-guo |
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| Affiliation: | 1. College of Chemistry and Chemical Engineering;Henan University;Kaifeng;Henan 475004;China;2. State Key Lab. Biochemical Engineering;Institute of Process Engineering;Chinese Academy of Sciences;Beijing 100190;China |
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| Abstract: | Molecularly imprinted polymer was synthesized with Rifampicin (RFP) as template molecule, methacrylic acid as functional monomers and ethylene dimethacrylate as crosslinker. The polymer was investigated in equilibrium binding experiment and Scatchard analysis to evaluate the binding characteristics and recognition mechanism of RFP molecular imprinted polymer in aqueous solution. Scatchard analysis showed that two classes of binding sites were produced in the polymer matrix under the studied concentration. T... |
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| Keywords: | molecularly imprinted polymer Rifampicin molecular recognition selectivity |
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