| 性激素三孢酸在类胡萝卜素生产菌三孢布拉氏霉中的合成代谢研究进展 |
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| 引用本文： | 张晓晖,苏思思,王文雅,袁其朋,李强. 性激素三孢酸在类胡萝卜素生产菌三孢布拉氏霉中的合成代谢研究进展[J]. 化工学报, 2016, 67(5): 1654-1664. DOI: 10.11949/j.issn.0438-1157.20151591 |
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| 作者姓名： | 张晓晖 苏思思 王文雅 袁其朋 李强 |
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| 作者单位： | 1.北京化工大学生命科学与技术学院, 北京 100029;2.清华大学化学工程系, 北京 100084 |
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| 基金项目： | 国家自然科学基金项目(21176018,21576153);国家高技术研究发展计划项目(2012AA02A701,2015AA021001)。 |
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| 摘 要： | 类胡萝卜素是重要的精细化学品,三孢布拉氏霉是发酵法生产类胡萝卜素的常用菌种。近年来研究者对影响三孢布拉氏霉类胡萝卜素产量的影响因素做了大量的研究,结果显示三孢酸是最重要的影响因子之一。本文根据国内外研究进展,从发酵法生产类胡萝卜素的研究现状、三孢酸类化合物的结构及其生理功能、三孢酸合成途径研究及三孢酸合成途径中的分子机制等几个方面做了综述报告。
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| 关 键 词： | 三孢酸 三孢布拉氏霉 类胡萝卜素 毛霉目真菌 β-胡萝卜素 |
| 收稿时间： | 2015-10-20 |
| 修稿时间： | 2015-12-13 |
Advances in sexual hormone trisporic acid biosynthesis in carotenoids producing Blakeslea trispora |
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| ZHANG Xiaohui,SU Sisi,WANG Wenya,YUAN Qipeng,LI Qiang. Advances in sexual hormone trisporic acid biosynthesis in carotenoids producing Blakeslea trispora[J]. Journal of Chemical Industry and Engineering(China), 2016, 67(5): 1654-1664. DOI: 10.11949/j.issn.0438-1157.20151591 |
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| Authors: | ZHANG Xiaohui SU Sisi WANG Wenya YUAN Qipeng LI Qiang |
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| Affiliation: | 1.College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China;2.Department of Chemical Engineering, Tsinghua University, Beijing 100084, China |
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| Abstract: | Given that carotenoids are important fine chemicals, the Blakeslea trispora is receiving increasing attention since its higher industrial production of carotenoids. Numerous factors could affect the carotenoids production in Blakeslea trispora, among which the trisporic acid is one of the uttermost importance. In the present paper, the advances of biosynthesis of trisporic acid were reviewed, including summary of carotenoids production by fermentation, structure and biological function of trisporoids, biosynthetic pathway of trisporic acid and molecular biology of trisporic acid biosynthesis. |
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| Keywords: | trisporic acid Blakeslea trispora carotenoids Mucorales fungi β-carotene |
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