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Fuzzy risk assessment of mortality after coronary surgery using combination of adaptive neuro‐fuzzy inference system and K‐means clustering
Authors:Mahyar Taghizadeh Nouei  Ali Vahidian Kamyad  MahmoodReza Sarzaeem  Somayeh Ghazalbash
Affiliation:1. Department of Applied Mathematics, School of Mathematical Sciences, Ferdowsi University of Mashhad, International Campus, Mashhad, Iran;2. Cardiac Surgery and Transplantation Research Center (CTRC), Shariati Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran
Abstract:In this paper, a fuzzy expert system based on adaptive neuro‐fuzzy inference system (ANFIS) is introduced to assess the mortality after coronary bypass surgery. In preprocessing phase, the attributes were reduced using a univariant analysis in order to make the classifier system more effective. Prognostic factors with a p‐value of less than 0.05 in chi‐square or t‐student analysis were given to inputs ANFIS classifier. The correct diagnosis performance of the proposed fuzzy system was calculated in 824 samples. To demonstrate the usefulness of the proposed system, the study compared the performance of fuzzy system based on ANFIS method through the binary logistic regression with the same attributes. The experimental results showed that the fuzzy model (accuracy: 96.4%; sensitivity: 66.6%; specificity: 97.2%; and area under receiver operating characteristic curve: 0.82) consistently outperformed the logistic regression (accuracy: 89.4%; sensitivity: 47.6%; specificity: 89.4%; and area under receiver operating characteristic curve: 0.62). The obtained classification accuracy of fuzzy expert system was very promising with regard to the traditional statistical methods to predict mortality after coronary bypass surgery such as binary logistic regression model.
Keywords:fuzzy expert system  risk assessment  coronary artery disease  neuro‐fuzzy inference system
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