| 酵母细胞微囊化水杨酸甲酯 |
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| 引用本文： | 王金宇,李淑芬,田松江. 酵母细胞微囊化水杨酸甲酯[J]. 化工学报, 2006, 57(4): 908-911 |
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| 作者姓名： | 王金宇 李淑芬 田松江 |
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| 作者单位： | 天津大学化工学院绿色合成与转化教育部重点实验室,天津,300072;天津大学化工学院绿色合成与转化教育部重点实验室,天津,300072;天津大学化工学院绿色合成与转化教育部重点实验室,天津,300072 |
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| 摘 要： | 以灭活的干酵母细胞为囊壁材料制备水杨酸甲酯微囊.研究了包埋温度、心材比、包埋时间等因素对微囊制备效果的影响.实验结果表明，在包埋温度70℃ 、心材比2 ml•g-1、包埋时间6 h条件下，水杨酸甲酯包埋率可以达到48.58%.这种新型的药物微囊化方法，具有制备过程简单、包埋率高、不引入有机溶剂的特点.
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| 关 键 词： | 微囊化 干酵母 水杨酸甲酯 包埋率 |
| 文章编号： | 0438-1157（2006）04-0908-04 |
| 收稿时间： | 2005-07-04 |
| 修稿时间： | 2005-07-042005-11-27 |
Microencapsulation of methyl salicylate by utilizing yeast cell |
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| WANG Jinyu,LI Shufen,TIAN Songjiang. Microencapsulation of methyl salicylate by utilizing yeast cell[J]. Journal of Chemical Industry and Engineering(China), 2006, 57(4): 908-911 |
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| Authors: | WANG Jinyu LI Shufen TIAN Songjiang |
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| Abstract: | The microcapsule of methyl salicylate（MS）was prepared by utilizing dried yeast(S. cerevisiae)cell deactivated by pretreating as wall material. The effects of encapsulating temperature,MS to yeast ratio and encapsulating time on the microencapsulation of MS were investigated. The results showed that the yield of encapsulated MS could reach 48.58% under the conditions of encapsulating temperature of 70℃,MS to yeast ratio of 2 ml•g-1 and encapsulating time of 6 h. By means of the novel pharmaceutical microencapsulation, the process was simple and efficient and was free from contamination by organic solvent. |
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| Keywords: | microencapsulation dried yeast methyl salicylate yield of encapsulated MS |
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