An efficient approach for brain image (tissue) compression based on the position of the brain tumor

Medical image processing plays an important role in brain tissue detection and segmentation. In this paper, a computer aided detection of brain tissue compression based on the estimation of the location of the brain tumor. The proposed system detects and segments the brain tissues and brain tumor using mathematical morphological operations. Further, the brain tissue with tumor is compressed using lossless compression technique and the brain tissue without tumor is compressed using lossy compression technique. The proposed method achieves 96.46% sensitivity, 99.20% specificity and 98.73% accuracy for the segmentation of white matter regions from the brain. The proposed method achieves 98.16% sensitivity, 99.36% specificity and 98.78% accuracy for the segmentation of cerebrospinal fluid (CSF) regions from the brain and also achieves 93.07% sensitivity, 98.79% specificity and 97.63% accuracy for the segmentation of grey matter regions from the brain. This paper focus the brain tissue compression based on the location of brain tumor. The grey matter of the brain is applied to lossless compression due to the presence of the tumor in grey matter of the brain. The proposed system achieves 29.23% of compression ratio for compressing the grey matter of the brain region. The white matter and CSF regions of the brain are applied to lossy compression due to the non‐presence of the tumor. The proposed system achieves 39.13% of compression ratio for compressing the white matter and also achieves 37.5% of compression ratio for compressing the CSF tissue. © 2016 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 26, 237–242, 2016     

Image registration-based brain tumor detection and segmentation using ANFIS classification approach

Abnormal cells in human brain lead to the development of tumors. Manual detection of this tumor region is a time-consuming process. Hence, this paper proposes an efficient and automated computer-aided methodology for brain tumor detection and segmentation using image registration technique and classification approaches. This proposed work consists of the following modules: image registration, contourlet transform, and feature extraction with feature normalization, classification, and segmentation. The extracted features are optimized using genetic algorithm, and then an adaptive neuro-fuzzy inference system classification approach is used to classify the features for the detection and segmentation of tumor regions in brain magnetic resonance imaging. A quantitative analysis is performed to evaluate the proposed methodology for brain tumor detection using sensitivity, specificity, segmentation accuracy, precision, and Dice similarity coefficient.     

A computer‐aided approach for meningioma brain tumor detection using CANFIS classifier

Abnormal growth of cells in brain leads to the formation of tumors in brain. The earlier detection of the tumors in brain will save the life of the patients. Hence, this article proposes a computer‐aided fully automatic methodology for brain tumor detection using Co‐Active Adaptive Neuro Fuzzy Inference System (CANFIS) classifier. The internal region of the brain image is enhanced using image normalization technique and further contourlet transform is applied on the enhanced brain image for the decomposition with different scales. The grey level and heuristic features are extracted from the decomposed coefficients and these features are trained and classified using CANFIS classifier. The performance of the proposed brain tumor detection is analyzed in terms of classification accuracy, sensitivity, specificity, and segmentation accuracy.     

基于卷积神经网络模型的遥感图像分类

研究了遥感图像的分类,针对遥感图像的支持向量机(SVM)等浅层结构分类模型特征提取困难、分类精度不理想等问题,设计了一种卷积神经网络(CNN)模型,该模型包含输入层、卷积层、全连接层以及输出层,采用Soft Max分类器进行分类。选取2010年6月6日Landsat TM5富锦市遥感图像为数据源进行了分类实验,实验表明该模型采用多层卷积池化层能够有效地提取非线性、不变的地物特征,有利于图像分类和目标检测。针对所选取的影像,该模型分类精度达到94.57%,比支持向量机分类精度提高了5%,在遥感图像分类中具有更大的优势。     

Superpixel with nanoscale imaging and boosted deep convolutional neural network concept for lung tumor classification

Lung tumor is a complex illness caused by irregular lung cell growth. Earlier tumor detection is a key factor in effective treatment planning. When assessing the lung computed tomography, the doctor has many difficulties when determining the precise tumor boundaries. By offering the radiologist a second opinion and helping to improve the sensitivity and accuracy of tumor detection, the use of computer-aided diagnosis could be near as effective. In this research article, the proposed Lung Tumor Detection Algorithm consists of four phases: image acquisition, preprocessing, segmentation, and classification. The Advance Target Map Superpixel-based Region Segmentation Algorithm is proposed for segmentation purposes, and then the tumor region is measured using the nanoimaging theory. Using the concept of boosted deep convolutional neural network yields 97.3% precision, image recognition can be achieved. In the types of literature with the current method, which shows the study's proposed efficacy, the implementation of the proposed approach is found dramatically.     

Dual‐pathway DenseNets with fully lateral connections for multimodal brain tumor segmentation

Multimodal medical image data provide different structured and functional information, which helps segment brain tumor and gets a reliable and accurate diagnosis. Segmenting brain tumors in magnetic resonance imaging (MRI) is a challenging task because brain tumors can be at any location with changeable shape and size. Existing deep neural networks for brain tumor segmentation use few connections to fuse multilevel information. To make use of multilevel information from multimodal MRIs, we propose dual‐pathway DenseNets with fully lateral connections (DP‐DenseNets), a three‐dimensional (3D) fully convolutional neural network that uses dense connectivity to construct dual‐pathway architecture to multimodal brain tumor segmentation problem. Each two similar imaging modalities have a pathway, for one thing, the bottom‐up pathway with dense connectivity is developed for extracting features; another, the top‐down pathway concatenates the features of the bottom‐up pathway in all layers. Dual pathways with different loss functions and fully lateral connectivity from the bottom‐up pathway to the top‐down pathway provide an abundant combination of different levels of features. Comparing to these fusion schemes such as input‐level fusion and later‐level fusion, this architecture leverages semantics from low to high levels, which is provided by fully lateral connectivity. Our model is evaluated on the dataset from Brain Tumor Segmentation Challenge 2017 (BRATS 2017), and the experiments show that our method achieves better performance than other 3D networks.     

An intelligent system for gastrointestinal polyp detection in endoscopic video using fusion of bidimensional empirical mode decomposition and convolutional neural network features

This paper presents an intelligent system for gastrointestinal polyp detection in endoscopic video. Video endoscopy is a popular diagnostic modality in assessing the gastrointestinal polyps. But the accuracy of diagnosis mostly depends on doctors' experience that is crucial to detect polyps in many cases. Computer-aided polyp detection is promising to reduce the miss detection rate of polyp and thus improve the accuracy of diagnosis results. The proposed method illustrates an automatic system based on a new color feature extraction scheme as a support for gastrointestinal polyp detection. The scheme is the combination of color empirical mode decomposition features and convolutional neural network features extracted from video frames. The features are fed into a linear support vector machine to train the classifier. Experiments on standard public databases show that the proposed scheme outperforms the previous conventional methods, gaining accuracy of 99.53%, sensitivity of 99.91%, and specificity of 99.15%.     

Multimodal brain tumor detection and classification using deep saliency map and improved dragonfly optimization algorithm

In the last decade, there has been a significant increase in medical cases involving brain tumors. Brain tumor is the tenth most common type of tumor, affecting millions of people. However, if it is detected early, the cure rate can increase. Computer vision researchers are working to develop sophisticated techniques for detecting and classifying brain tumors. MRI scans are primarily used for tumor analysis. We proposed an automated system for brain tumor detection and classification using a saliency map and deep learning feature optimization in this paper. The proposed framework was implemented in stages. In the initial phase of the proposed framework, a fusion-based contrast enhancement technique is proposed. In the following phase, a tumor segmentation technique based on saliency maps is proposed, which is then mapped on original images based on active contour. Following that, a pre-trained CNN model named EfficientNetB0 is fine-tuned and trained in two ways: on enhanced images and on tumor localization images. Deep transfer learning is used to train both models, and features are extracted from the average pooling layer. The deep learning features are then fused using an improved fusion approach known as Entropy Serial Fusion. The best features are chosen in the final step using an improved dragonfly optimization algorithm. Finally, the best features are classified using an extreme learning machine (ELM). The experimental process is conducted on three publically available datasets and achieved an improved accuracy of 95.14, 94.89, and 95.94%, respectively. The comparison with several neural nets shows the improvement of proposed framework.     

A deep learning model integrating convolution neural network and multiple kernel K means clustering for segmenting brain tumor in magnetic resonance images

In medical imaging, segmenting brain tumor becomes a vital task, and it provides a way for early diagnosis and treatment. Manual segmentation of brain tumor in magnetic resonance (MR) images is a time‐consuming and challenging task. Hence, there is a need for a computer‐aided brain tumor segmentation approach. Using deep learning algorithms, a robust brain tumor segmentation approach is implemented by integrating convolution neural network (CNN) and multiple kernel K means clustering (MKKMC). In this proposed CNN‐MKKMC approach, classification of MR images into normal and abnormal is performed by CNN algorithm. At next, MKKMC algorithm is employed to segment the brain tumor from the abnormal brain image. The proposed CNN‐MKKMC algorithm is evaluated both visually and objectively in terms of accuracy, sensitivity, and specificity with the existing segmentation methods. The experimental results demonstrate that the proposed CNN‐MKKMC approach yields better accuracy in segmenting brain tumor with less time cost.     

A fuzzy logic‐based meningioma tumor detection in magnetic resonance brain images using CANFIS and U‐Net CNN classification

This article develops a methodology for meningioma brain tumor detection process using fuzzy logic based enhancement and co‐active adaptive neuro fuzzy inference system and U‐Net convolutional neural network classification methods. The proposed meningioma tumor detection process consists of the following stages as, enhancement, feature extraction, and classifications. The enhancement of the source brain image is done using fuzzy logic and then dual tree‐complex wavelet transform is applied to this enhanced image at different levels of scale. The features are computed from the decomposed sub band images and these features are further classified using CANFIS classification method which identifies the meningioma brain image from nonmeningioma brain image. The performance of the proposed meningioma brain tumor detection and segmentation system is analyzed in terms of sensitivity, specificity, segmentation accuracy, and Dice coefficient index with detection rate.     

CANFIS based glioma brain tumor classification and retrieval system for tumor diagnosis

Brain tumor classification and retrieval system plays an important role in medical field. In this paper, an efficient Glioma Brain Tumor detection and its retrieval system is proposed. The proposed methodology consists of two modules as classification and retrieval. The classification modules are designed using preprocessing, feature extraction and tumor detection techniques using Co‐Active Adaptive Neuro Fuzzy Inference System (CANFIS) classifier. The image enhancement can be achieved using Heuristic histogram equalization technique as preprocessing and further texture features as Local Ternary Pattern (LTP) features and Grey Level Co‐occurrence Matrix (GLCM) features are extracted from the enhanced image. These features are used to classify the brain image into normal and abnormal using CANFIS classifier. The tumor region in abnormal brain image is segmented using normalized graph cut segmentation algorithm. The retrieval module is used to retrieve the similar segmented tumor regions from the dataset for diagnosing the tumor region using Euclidean algorithm. The proposed Glioma Brain tumor classification methodology achieves 97.28% sensitivity, 98.16% specificity and 99.14% accuracy. The proposed retrieval system achieves 97.29% precision and 98.16% recall rate with respect to ground truth images.     

Fully automatic multisegmentation approach for magnetic resonance imaging brain tumor detection using improved region-growing and quasi-Monte Carlo-expectation maximization algorithm

Magnetic resonance imaging (MRI) is widely used in the medical field, especially for detecting serious abnormalities affecting the organs of the human body, such as tumors. Automatic detection of tumors needs high-performance recognition techniques. In this paper, we have developed a new automatic method based on the multisegmentation of brain tumor region. We used an improved region-growing algorithm, which is based on quasi-Monte Carlo and expectation maximization methods to define the desired classes. Several metrics were calculated to evaluate the performance of our technique. The fully automatic multisegmentation approach, developed in this study, showed good performance, and it can offer a new option to replace conventional techniques used for tumor detection in MRI images.     

Deep learning and machine learning-based early survival predictions of glioblastoma patients using pre-operative three-dimensional brain magnetic resonance imaging modalities

To propose and implement an automated machine learning (ML) based methodology to predict the overall survival of glioblastoma multiforme (GBM) patients. In the proposed methodology, we used deep learning (DL) based 3D U-shaped Convolutional Neural Network inspired encoder-decoder architecture to segment the brain tumor. Further, feature extraction was performed on these segmented and raw magnetic resonance imaging (MRI) scans using a pre-trained 2D residual neural network. The dimension-reduced principal components were integrated with clinical data and the handcrafted features of tumor subregions to compare the performance of regression-based automated ML techniques. Through the proposed methodology, we achieved the mean squared error (MSE) of 87 067.328, median squared error of 30 915.66, and a SpearmanR correlation of 0.326 for survival prediction (SP) with the validation set of Multimodal Brain Tumor Segmentation 2020 dataset. These results made the MSE far better than the existing automated techniques for the same patients. Automated SP of GBM patients is a crucial topic with its relevance in clinical use. The results proved that DL-based feature extraction using 2D pre-trained networks is better than many heavily trained 3D and 2D prediction models from scratch. The ensembled approach has produced better results than single models. The most crucial feature affecting GBM patients' survival is the patient's age, as per the feature importance plots presented in this work. The most critical MRI modality for SP of GBM patients is the T2 fluid attenuated inversion recovery, as evident from the feature importance plots.     

基于协同采样主动学习的恶意代码检测

研究了基于机器学习分类算法的恶意代码检测,考虑到目前主要采用传统分类方法对恶意代码进行分类识别,这些方法需要通过学习大量标记样本来获得精准的分类器模型,然而样本标记工作只有少数专家才能完成,导致标记样本往往不足,致使分类结果准确率不高,提出了一种基于协同采样的主动学习方法。运用这种学习方法,仅需少量标记样本即可有效识别出恶意代码。实验证明,相对于传统的恶意代码分类方法,该方法能够显著提升分类准确率和泛化性能。     

Multimodal magnetic resonance imaging for Alzheimer's disease diagnosis using hybrid features extraction and ensemble support vector machines

Magnetic resonance imaging (MRI) is increasingly used in the diagnosis of Alzheimer's disease (AD) in order to identify abnormalities in the brain. Indeed, cortical atrophy, a powerful biomarker for AD, can be detected using structural MRI (sMRI), but it cannot detect impairment in the integrity of the white matter (WM) preceding cortical atrophy. The early detection of these changes is made possible by the novel MRI modality known as diffusion tensor imaging (DTI). In this study, we integrate DTI and sMRI as complementary imaging modalities for the early detection of AD in order to create an effective computer-assisted diagnosis tool. The fused Bag-of-Features (BoF) with Speeded-Up Robust Features (SURF) and modified AlexNet convolutional neural network (CNN) are utilized to extract local and deep features. This is applied to DTI scalar metrics (fractional anisotropy and diffusivity metric) and segmented gray matter images from T1-weighted MRI images. Then, the classification of local unimodal and deep multimodal features is first performed using support vector machine (SVM) classifiers. Then, the majority voting technique is adopted to predict the final decision from the ensemble SVMs. The study is directed toward the classification of AD versus mild cognitive impairment (MCI) versus cognitively normal (CN) subjects. Our proposed method achieved an accuracy of 98.42% and demonstrated the robustness of multimodality imaging fusion.     

A rapid automatic brain tumor detection method for MRI images using modified minimum error thresholding technique

This proposed work is aimed to develop a rapid automatic method to detect the brain tumor from T2‐weighted MRI brain images using the principle of modified minimum error thresholding (MET) method. Initially, modified MET method is applied to produce well segmented and sub‐structural clarity for MRI brain images. Further, using FCM clustering the appearance of tumor area is refined. The obtained results are compared with corresponding ground truth images. The quantitative measures of results were compared with the results of those conventional methods using the metrics predictive accuracy (PA), dice coefficient (DC), and processing time. The PA and DC values of the proposed method attained maximum value and processing time is minimum while compared to conventional FCM and k‐means clustering techniques. This proposed method is more efficient and faster than the existing segmentation methods in detecting the tumor region from T2‐weighted MRI brain images. © 2015 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 25, 77–85, 2015     

Automatic detection of brain tumor in magnetic resonance images using multi‐texton histogram and support vector machine

Segmentation is the process of labeling objects in image data. It is a decisive phase in several medical imaging processing tasks for operation planning, radio therapy or diagnostics, and widely useful for studying the differences of healthy persons and persons with tumor. Magnetic Resonance Imaging brain tumor segmentation is a complicated task due to the variance and intricacy of tumors. In this article, a tumor segmentation scheme is presented, which focuses on the structural analysis on both tumorous and normal tissues. Our proposed method hits the target with the aid of the following major steps: (i) Tumor Region Location, (ii) Feature Extraction using Multi‐texton Technique, and (iii) Final Classification using support vector machine (SVM). The results for the tumor detection are validated through evaluation metrics such as, sensitivity, specificity, and accuracy. The comparative analysis is carried out by Radial Basis Function neural network and Feed Forward Neural Network. The obtained results depict that the proposed Multi‐texton histogram and support vector machine based brain tumor detection approach is more robust than the other classifiers in terms of sensitivity, specificity, and accuracy. © 2013 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 23, 97–103, 2013     

A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy

A new classification approach was developed to improve the noninvasive diagnosis of brain tumors. Within this approach, information is extracted from magnetic resonance imaging and spectroscopy data, from which the relative location and distribution of selected tumor classes in feature space can be calculated. This relative location and distribution is used to select the best information extraction procedure, to identify overlapping tumor classes, and to calculate probabilities of class membership. These probabilities are very important, since they provide information about the reliability of classification and might provide information about the heterogeneity of the tissue. Classification boundaries were calculated by setting thresholds for each investigated tumor class, which enabled the classification of new objects. Results on histopathologically determined tumors are excellent, demonstrated by spatial maps showing a high probability for the correctly identified tumor class and, moreover, low probabilities for other tumor classes.     

Cuckoo Optimized Convolution Support Vector Machine for Big Health Data Processing

Big health data collection and storing for further analysis is a challenging task because this knowledge is big and has many features. Several cloud-based IoT health providers have been described in the literature previously. Furthermore, there are a number of issues related to time consumed and overall network performance when it comes to big data information. In the existing method, less performed optimization algorithms were used for optimizing the data. In the proposed method, the Chaotic Cuckoo Optimization algorithm was used for feature selection, and Convolutional Support Vector Machine (CSVM) was used. The research presents a method for analyzing healthcare information that uses in future prediction. The major goal is to take a variety of data while improving efficiency and minimizing process time. The suggested method employs a hybrid method that is divided into two stages. In the first stage, it reduces the features by using the Chaotic Cuckoo Optimization algorithm with Levy flight, opposition-based learning, and distributor operator. In the second stage, CSVM is used which combines the benefits of convolutional neural network (CNN) and SVM. The CSVM modifies CNN’s convolution product to learn hidden deep inside data sources. For improved economic flexibility, greater protection, greater analytics with confidentiality, and lower operating cost, the suggested approach is built on fog computing. Overall results of the experiments show that the suggested method can minimize the number of features in the datasets, enhances the accuracy by 82%, and decrease the time of the process.     

A lightweight deep learning model for retinal optical coherence tomography image classification

Automated retinal disease detection and grading is one of the most researched areas in medical image analysis. In recent years, Deep Learning models have attracted much attention in this field. Hence, in this paper, we present a Deep Learning-based, lightweight, fully automated end-to-end diagnostic system for the detection of the two major retinal diseases, namely diabetic macular oedema (DME) and drusen macular degeneration (DMD). Early detection of these diseases is important to prevent vision impairment. Optical coherence tomography (OCT) is the main imaging technique for detecting these diseases. The model proposed in this work is based on residual blocks and channel attention modules. The performance of the model is evaluated using the publicly available Mendeley OCT dataset and the Duke dataset. We were able to achieve a classification accuracy of 99.5% in the Mendeley test dataset and 94.9% in the Duke dataset with the proposed model. For the application, we performed an extensive evaluation of pre-trained models (LeNet, AlexNet, VGG-16, ResNet50 and SE-ResNet). The proposed model has a much smaller number of trainable parameters and shows superior performance compared to existing methods.