Percutaneous transhepatic radiomanometry of the bile ducts (PTC-manometry) (author's transl)

Method and first results of the PTC-manometry are shown in 32 cases. Low residual pressures in bilio-digestive anastomosis and high results both in incomplete bile obstruction and in anicteric patients with incomplete stenosis of the common bile duct and with papillary stenosis suggest a clinical importance. In connection with clinical symptoms and x-ray results it is possible to give informations already preoperatively which we could got only by intraoperative radiomanometry till now. There was no correlation between the maximum size of the common bile duct and the residual pressure.     

Dumping-prophylaxis (author's transl)

The dumping syndrome is due to a vigorous reflex distension of the jejunum, caused by the stomach violently evacuating its contents. The aim of treatment is to overcome the drastic evacuation by restoring the rhythmic peristalsis of the stomach (eukinetics). This can be achieved by a special diet. Every meal should begin with well chewed solids (pulp) and avoid all fluids. With a well organised medical staff a complete success can be achieved. Surgical measures in Dumping can be avoided.     

Arabinosyladenine in ophthalmology (author's transl)

Arabinosyladenine (Ara-A) is an antiviral compound employed for ophthalmological lesions in the form of a 3 p. cent ointment. This purine nucleoside has been shown to possess antiviral activity against several ADN viruses, including herpes simplex virus, but it is ineffective against ARN viruses. Its action in superficial herpetic keratitis is comparable with that of idoxuridine, tolerance to the two compounds being almost identical. Ara-A is of value for treating superficial keratitis lesions not responding to idoxuridine. The weak intra-ocular penetration of Ara-A explains its lack of efficacy in stromal keratitis and herpetic kerato-uveitis, forms in which certain analogues of Ara-A could be beneficial.     

Dysphonia in acromegaly (author's transl)

Acromegalic dysphonia is described in a series of 80 acromegalic patients. Subjective dysphonia was observed in most patients, objective dysphonia, however, wasnoted in only 50% of the cases. The patients with objective dysphonia usually had progenia, moderate to high acromegalic activity and duration of disease of more than five years. The different factors of importance for the development of acromegalic dysphonia are summarized.     

Conisation and fertility (author's transl)

Long-term observation by defined criteria of 121 women who had undergone conisation gave 56 pregnancies in 49 patients. The pregnancy rate established, with due consideration of contraception, other causes of sterility, and sexual activity, was about 75 per cent. Twenty-five deliveries were analysed. Forty per cent of them were premature births, with some of the newborns being of extremely low birth weight, which supported the conclusion that pregnancies following conisation should be given high-risk rating and, generally, lead to hospitalisation of the women concerned.     

Sarcosporidiosis in sheep (author's transl)

Histological examination of the masseter muscle, diaphragm, oseophagus and heart showed that about 18 per cent of approximately eight-month-old sheep in the Netherlands were infected with Sarcocystis. The masseter muscle obviously was the site of predilection.     

Endoscopic-radiologic cholangio-pancreaticography (author's transl)

Results of 408 own endoscropic-radiologic cholangio-pancreatico-graphies are presented, indications and diagnostic relevance of the method are discussed. Low rate of complications and its high diagnostic value are reasons for ERCP's clinical importance even as a routine procedure at gastro-enterological centers. In the future, cytological, immunological and biochemical analysis of juices and aspirates as well as endoscopic surgery will contribute to an even wider clinical use of the method. In 337 patients (82.6%) cannulation of the papilla of Vater and visualization of one or both duct systems were successful. In 198 cases with visualization of ducts (58.8%) pathological lesions were found. Thus observation of indications and contra-indications of ERCP is documented, of a method, which is not too risky, but relatively expensive and difficult to employ.